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M22601

Sigma-Aldrich

1-(2-Methoxyphenyl)piperazine

98%

Sinonimo/i:

1-(2-Methoxyphenyl)piperazine, 1-(o-Anisyl)piperazine, 1-(o-Methoxyphenyl)piperazine, N-(2-Methoxyphenyl)piperazine, N-(o-Methoxyphenyl)piperazine, o-Methoxyphenylpiperazine

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About This Item

Formula empirica (notazione di Hill):
C11H16N2O
Numero CAS:
35386-24-4
Peso molecolare:
192.26
Beilstein:
167888
Numero CE:
252-537-7
Numero MDL:
MFCD00005958
Codice UNSPSC:
12352100
ID PubChem:
24896714
NACRES:
NA.22

Saggio

98%

Indice di rifrazione

n20/D 1.575 (lit.)

P. ebollizione

130-133 °C/0.1 mmHg (lit.)

Punto di fusione

35-40 °C (lit.)

Densità

1.095 g/mL at 25 °C (lit.)

Stringa SMILE

COc1ccccc1N2CCNCC2

InChI

1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
VNZLQLYBRIOLFZ-UHFFFAOYSA-N

Informazioni sul gene

mouse ... Htr3a(15561)
rat ... Adra1a(29412) , Drd2(24318) , Htr1a(24473) , Htr2a(29595) , Htr7(65032)

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Applicazioni

1-(2-Methoxyphenyl)piperazine can be used:
  • To functionalize pyrazolylvinyl ketones via Aza-Michael addition reaction.
  • To prepare cyclic amine substituted Tröger′s base derivatives.
  • To prepare functionalized bis(mercaptoimidazolyl)borates by reacting with the activated ester, [(1-methyl-2-mercaptoimidazol-5-yl)carbonyl]succinimide.

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H314

Classi di pericolo

Eye Dam. 1 - Skin Corr. 1B

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

230.0 °F - closed cup

Punto d’infiammabilità (°C)

110 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
STBJ5077
STBG9925
STBF5530V
STBD0689V
STBC9569V

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Hartmut Henneken et al.
Journal of environmental monitoring : JEM, 8(10), 1014-1019 (2007-01-24)
Diffusive sampling of methyl isocyanate (MIC) on 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole (NBDPZ)-coated glass fibre (GF) filters is strongly affected by high relative humidity (RH) conditions. It is shown that the humidity interference is a physical phenomenon, based on displacement of reagent from the
Christian Mattsson et al.
International journal of hygiene and environmental health, 211(3-4), 458-462 (2007-09-18)
Occupational exposure to toluene diisocyanate (TDI) is a known occupational hazard and the occupational exposure limits in air are very low. One of the most common methods to monitor exposure to isocyanates is to sample air through filters impregnated with
Rhenium (I) tricarbonyl complexes with mercaptoimidazolylborate ligands bearing piperazine fragments
Garcia R, et al.
J. Chem. Soc., Dalton Trans., 6(22), 4236-4241 (2002)
P Molander et al.
Journal of chromatography. A, 892(1-2), 67-74 (2000-10-25)
A temperature-programmed packed capillary LC method with large-volume injection on-column focusing has been developed for screening and determination of 1-(2-methoxyphenyl)piperazine derivatives of airborne toluene-2,4-diisocyanate, toluene-2,6-diisocyanate, hexamethylenediisocyanate and methylenebisphenyl-4,4-diisocyanate, based on sampling methods described in MDHS 25/3. Injection volumes up to
L Pawłowski
Polish journal of pharmacology and pharmacy, 35(4), 319-326 (1983-01-01)
1-(o-methoxyphenyl)-piperazine (o-MPP) is regarded as an antagonist of the dopamine receptor. Its effects were studied for the hind limb flexor reflex in the spinal rat, the body temperature in rats maintained at ambient temperature of 28 degrees C and stereotypy
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