913979

Biotin-Thalidomide

≥95%

• Sinonimo/i: N¹-(4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)-N⁵-(15-oxo-19-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-14-azanonadecyl)glutaramide, Biotin-conjugated thalidomide, bio-Thal
• Formula empirica (notazione di Hill): C₄₄H₆₄N₈O₁₃S
• Numero CAS: 2230857-87-9
• Peso molecolare: 945.09
• Numero MDL: MFCD32851674
• Codice UNSPSC: 12352200
• NACRES: NA.22

Proprietà

• ligand: thalidomide
• Livello qualitativo: 100
• Saggio: ≥95%
• Stato: powder
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3OCC(NCCCCNC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]4[C@](NC(N5)=O)([H])[C@]5([H])CS4)=O)=O)=O)=O)=O)NC1=O
• InChI: 1S/C44H64N8O13S/c53-34(12-2-1-11-33-40-30(28-66-33)49-44(61)51-40)46-19-7-21-62-23-25-64-26-24-63-22-8-20-47-36(55)14-6-13-35(54)45-17-3-4-18-48-38(57)27-65-32-10-5-9-29-39(32)43(60)52(42(29)59)31-15-16-37(56)50-41(31)58/h5,9-10,30-31,33,40H,1-4,6-8,11-28; UCTZYEDSVDZJQR-NTZPKYJMSA-N

Descrizione

Applicazioni

Biotin-Thalidomide (bio-Thal) is a cereblon affinity probe for PROTAC^® and targeted protein degradation research. Bio-Thal can be used in cereblon (CRBN) binding and displacement assays for protein degrader validation experiments, CRBN ligand discovery, competition analyses, or where enrichment of CRBN complexes is required.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Altre note

The dTAG system for immediate and target-specific protein degradation

Note legali

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable