638455
Trifluoromethanesulfonamide
95%
Sinonimo/i:
1,1,1-Trifluoromethanesulfonamide, Trifluoromethylsulfonamide
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About This Item
Formula condensata:
CF3SO2NH2
Numero CAS:
Peso molecolare:
149.09
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
![N-Methyl bis[(trifluoromethyl)sulfonyl]imide ≥90.0% (GC)](/deepweb/assets/sigmaaldrich/product/structures/293/464/eefedfb1-fedb-4509-a339-48035f47c0eb/640/eefedfb1-fedb-4509-a339-48035f47c0eb.png)
Saggio
95%
Stato
solid
Punto di fusione
120-124 °C (lit.)
Gruppo funzionale
fluoro
Stringa SMILE
NS(=O)(=O)C(F)(F)F
InChI
1S/CH2F3NO2S/c2-1(3,4)8(5,6)7/h(H2,5,6,7)
KAKQVSNHTBLJCH-UHFFFAOYSA-N
Informazioni sul gene
human ... CA2(760)
Categorie correlate
Applicazioni
Trifluoromethanesulfonamide can undergo reaction with paraformaldehyde either in sulfuric acid to give the corresponding open chain and cyclic condensation products or in ethyl acetate to give the corresponding oxy-methylated products.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Gloves
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C J Lynch et al.
The Biochemical journal, 310 ( Pt 1), 197-202 (1995-08-15)
The role of carbonic anhydrase in de novo lipid synthesis was examined by measuring [1-14C]acetate incorporation into total lipids, fatty acids and non-saponifiable lipids in freshly isolated rat hepatocytes. Two carbonic anhydrase inhibitors, trifluoromethylsulphonamide (TFMS) and ethoxozolamide (ETZ) decreased incorporation
"Oxymethylation of trifluoromethanesulfonamide with paraformaldehyde in ethyl acetate"
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The arrangement of an ionic fluorophore in the crystalline state was regulated by the presence of various counter-ions and the effect on spectroscopic and self-association properties was studied. To do so, nine salts of berberine (i.e. a fluorescent natural alkaloid)
"Cascade transformations of trifluoromethanesulfonamide in reaction with formaldehyde"
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Human carbonic anhydrases (CAs) play crucial role in various physiological processes including carbon dioxide and hydrocarbon transport, acid homeostasis, biosynthetic reactions, and various pathological processes, especially tumor progression. Therefore, CAs are interesting targets for pharmaceutical research. The structure-activity relationships (SAR)
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