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Key Documents

457620

Sigma-Aldrich

Polyglycolide

inherent viscosity 1.4dL/g

Sinonimo/i:

PGA, Poly(glycolic acid)

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About This Item

Formula condensata:
(C2H4O3)n
Numero CAS:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23

Livello qualitativo

Forma fisica

solid

Tempo di degradazione

6-12 months

Viscosità intrinseca

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

Temp. transizione

Tm 220-230 °C

Solubilità

hexafluoroisopropanol: soluble

Densità

1.53 g/mL at 25 °C (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
AEMRFAOFKBGASW-UHFFFAOYSA-N

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Descrizione generale

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.

Applicazioni

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.
medical device

Proprietà fisiche

Biodegradable polymer

Nota sulla preparazione

To achieve solubility in hexafluoroisopropanol, melt crystalline product and quench with liquid nitrogen to change material to amorphous form.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Fast Synthesis of High-Molecular-Weight Polyglycolide Using Diphenyl Bismuth Bromide as Catalyst
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Articoli

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Contenuto correlato

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

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