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359661

Sigma-Aldrich

H-Lys(Boc)-OH

≥95%, for peptide synthesis

Sinonimo/i:

Nε-Boc-L-lysine

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About This Item

Formula condensata:
(CH3)3COCONH(CH2)4CH(NH2)COOH
Numero CAS:
2418-95-3
Peso molecolare:
246.30
Beilstein:
2417626
Numero MDL:
MFCD00037221
Codice UNSPSC:
12352209
ID PubChem:
24862097
NACRES:
NA.22

product name

H-Lys(Boc)-OH, ≥95%

Livello qualitativo

200

Saggio

≥95%

Forma fisica

powder

Attività ottica

[α]20/D +18°, c = 1 in acetic acid

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

250 °C (dec.) (lit.)

applicazioni

peptide synthesis

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(C)(C)OC(=O)NCCCC[C@H](N)C(O)=O

InChI

1S/C11H22N2O4/c1-11(2,3)17-10(16)13-7-5-4-6-8(12)9(14)15/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
VVQIIIAZJXTLRE-QMMMGPOBSA-N

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Descrizione generale

H-Lys(Boc)-OH also known as Nε-Boc-L-lysine, is commonly used in solution phase peptide synthesis.

Applicazioni

H-Lys(Boc)-OH can be used to prepare pentafluorophenyl esters which further used to synthesize β-peptides.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BGBC4904V
BGBC0757V
BCBF3869V
1452248V
1452248

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Xiang Gao et al.
Molecular pharmaceutics, 10(1), 187-198 (2012-12-19)
PEGylated lipopeptide surfactants carrying drug-interactive motifs specific for a peptide-nitroxide antioxidant, JP4-039, were designed and constructed to facilitate the solubilization of this drug candidate as micelles and emulsion nanoparticles. A simple screening process based on the ability that prevents the
Shuqin Han et al.
Carbohydrate polymers, 90(2), 1061-1068 (2012-07-31)
A new third generation amphiphilic glycodendrimer was synthesized from a stearylamide lysine dendrimer by condensation of the oligosaccharide moiety. By stepwise condensation and deprotection of di-boc lysine from a core of stearyl amide lysine, a third-generation stearylamide lysine dendrimer was
April Case et al.
Analytical biochemistry, 338(2), 237-244 (2005-03-05)
Tissue transglutaminase (TGase) is a Ca(2+)-dependent enzyme that catalyzes cross-linking of intracellular proteins through a mechanism that involves isopeptide bond formation between Gln and Lys residues. In addition to its transamidation activity, TGase can bind guanosine 5'-triphosphate (GTP) and does
Maria Moccia et al.
International journal of pharmaceutics, 397(1-2), 179-183 (2010-07-06)
A novel nucleic acid compaction device based on a positively-charged alpha,epsilon-poly-l-lysine was realized for the first time. The polycationic peptide was obtained by assembling Fmoc and Boc orthogonally protected l-lysine monomers by solid phase synthesis. The route to the novel
K Itakura et al.
Chemical research in toxicology, 14(5), 473-475 (2001-05-23)
It has been suggested that protein modifications by malondialdehyde (MDA), a major product of lipid peroxidation, contribute to the fluorescence formation of lipofuscin. Although early studies proposed an aminoenimine structure (RNHCH=CHCH=NR) formed from MDA and the epsilon-amino groups of the
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