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233412

Sigma-Aldrich

Ethyl (hydroxyimino)cyanoacetate

97%, for peptide synthesis

Sinonimo/i:

Ethyl cyano(hydroxyimino)acetate, Ethyl cyanoglyoxalate-2-oxime, Ethyl isonitrosocyanoacetate

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About This Item

Formula condensata:
NCC(=NOH)CO2C2H5
Numero CAS:
3849-21-6
Peso molecolare:
142.11
Beilstein:
774783
Numero CE:
223-351-3
Numero MDL:
MFCD00002112
Codice UNSPSC:
12352100
ID PubChem:
24853975
NACRES:
NA.22

Nome del prodotto

Ethyl (hydroxyimino)cyanoacetate, 97%

Livello qualitativo

200

Saggio

97%

Stato

solid

Punto di fusione

130-132 °C (lit.)

applicazioni

peptide synthesis

Gruppo funzionale

amine
ester
nitrile
oxime

Stringa SMILE

CCOC(=O)C(=N\O)\C#N

InChI

1S/C5H6N2O3/c1-2-10-5(8)4(3-6)7-9/h9H,2H2,1H3/b7-4+
LCFXLZAXGXOXAP-QPJJXVBHSA-N

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Descrizione generale

Ethyl (hydroxyimino)cyanoacetate is a potential replacement for zobenzotriazole and benzotriazole derivatives used in peptide synthesis.

Ethyl (hydroxyimino)cyanoacetate is also called as Oxyma. It is a highly efficient greener alternative for the amide and peptide synthesis.

Applicazioni

Ethyl (hydroxyimino)cyanoacetate has been used as an additive for the carbodiimide-mediated amide bond formation during established peptide synthesis method.For peptide synthesis grade material, please see product 851086.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCF4173
BCCD7896
BCCC9498
BCCB9815
BCCB1779

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COMU is a non-explosive coupling agent suitable for solution phase & solid phase peptide synthesis. Its activity meets or exceeds that of HATU and its water-soluble by-product are easily removed.

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