1176007
USP
地塞米松
United States Pharmacopeia (USP) Reference Standard
别名:
(11β,16α)-9-氟-11,17,21-三羟基-16-甲基孕甾-1,4-二烯-3,20-二酮, 9α-氟-16α-甲基-11β,17α,21-三羟基-1,4-妊娠双烯-3,20-二酮, 9α-氟-16α-甲基泼尼松龙, 泼尼松龙F
About This Item
推荐产品
生物源
synthetic
等級
pharmaceutical primary standard
agency
USP
蒸汽壓力
<0.0000001 kPa ( 25 °C)
API 家族
dexamethasone
包裝
pkg of 125 mg
製造商/商標名
USP
顏色
white
mp
262-264 °C (lit.)
溶解度
acetone: sparingly soluble
chloroform: slightly soluble
ethanol: sparingly soluble
ether: very slightly soluble
methanol: sparingly soluble
water: practically insoluble
應用
pharmaceutical (small molecule)
形式
neat
儲存溫度
2-8°C
SMILES 字串
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InChI
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI 密鑰
UREBDLICKHMUKA-CXSFZGCWSA-N
基因資訊
human ... NR3C1(2908)
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一般說明
應用
- Ciprofloxacin and Dexamethasone Otic Suspension
- Dexamethasone
- Dexamethasone Compounded Oral Suspension
- Dexamethasone Elixir
- Dexamethasone Injection
- Dexamethasone Ophthalmic Suspension
- Dexamethasone Oral Solution
生化/生理作用
分析報告
其他說明
相關產品
訊號詞
Danger
危險聲明
危險分類
Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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实验方案
A simple, precise and sensitive Reverse-Phase High Pressure Liquid Chromatography gradient method was adapted for traceability, homogeneity and total chromatographic analysis of Dexamethasone. The given experimental conditions follow the USP43-NF38 monograph method for Dexamethasone Assay and Organic Impurity Profiling. Dexamethasone, Betamethasone, Dexamethasone acetate and Desoximetasone were baseline resolved within 20 minutes using a Titan C18 UHPLC column (2.1 x 100 mm, 1.9 µm).
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