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應用
酿酒酵母中的酵母聚糖A用于:
- 用作阳性对照品,确定激活补体级联反应
- 检测呼吸爆发(RB)
- 评估热应激(HS)下,其对奶牛产奶性能、免疫力、热休克蛋白和凋亡相关基因表达的影响
- 用作克雷布斯-林格(Krebs-Ringer)磷酸盐(KRP)培养基中的刺激剂
- 诱导小鼠发生热痛觉过敏
- 用流式细胞仪
- 研究其对虹鳟鱼(Oncorhynchus mykiss)头肾白细胞的影响
生化/生理作用
酵母聚糖从酵母细胞壁制备,由蛋白质-碳水化合物复合体组成。可以用来诱导实验无菌性炎症。在巨噬细胞中,酵母聚糖诱导的应答包括诱导促炎细胞因子、花生四烯酸移动,蛋白磷酸化和肌醇磷酸形成。酵母聚糖A能够提高细胞周期蛋白D2水平,说明后者除增殖外还在巨噬细胞活化中起作用。酵母聚糖A能够加重注射半乳糖胺造成的急性肝脏损伤,表明除库普弗(Kupffer)细胞外,还有某些类型的非实质细胞参与酵母聚糖作用。酵母聚糖A(一种13β葡聚糖)能使有机粉尘引起的呼吸道疾病继续进展。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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