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Merck

X0750

Sigma-Aldrich

黄嘌呤核苷 二水合物

≥99%

别名:

9-β-D-呋喃核糖黄嘌呤

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About This Item

经验公式(希尔记法):
C10H12N4O6 · 2H2O
CAS号:
分子量:
320.26
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

生物源

synthetic (organic)

化驗

≥99%

形狀

powder

溶解度

1 M NH4OH: 50 mg/mL, clear, colorless to faintly yellow

SMILES 字串

O.O.OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3C(=O)NC(=O)Nc23

InChI

1S/C10H12N4O6.2H2O/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;;/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);2*1H2/t3-,5-,6-,9-;;/m1../s1

InChI 密鑰

ZCCPXSQIUORWCO-LGVAUZIVSA-N

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一般說明

黄嘌呤核苷由黄嘌呤环组成。它是嘌呤代谢产物,也是咖啡因生物合成的中间产物。

應用

黄嘌呤核苷二水合物可作为一维液相色谱分析(1D-LC)的测试品。

生化/生理作用

黄嘌呤核苷在嘌呤代谢中起关键作用。乳腺癌中存在高水平的黄嘌呤核苷分泌。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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The 6-oxopurine xanthine (Xan, neutral form 2,6-diketopurine) differs from the corresponding 6-oxopurines guanine (Gua) and hypoxanthine (Hyp) in that, at physiological pH, it consists of a approximately 1:1 equilibrium mixture of the neutral and monoanionic forms, the latter due to
Lucas Willmann et al.
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Cancer cells show characteristic effects on cellular turnover and DNA/RNA modifications leading to elevated levels of excreted modified nucleosides. We investigated the molecular signature of different subtypes of breast cancer cell lines and the breast epithelial cell line MCF-10A. Prepurification
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Analytical and bioanalytical chemistry, 407(13), 3555-3566 (2015-03-05)
Modified nucleosides derived from the RNA metabolism constitute an important chemical class, which are discussed as potential biomarkers in the detection of mammalian breast cancer. Not only the variability of modifications, but also the complexity of biological matrices such as

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