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品質等級
化驗
98%
mp
>300 °C (lit.)
溶解度
hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green
SMILES 字串
NC1=Nc2[nH]cnc2C(=O)N1
InChI
1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
InChI 密鑰
UYTPUPDQBNUYGX-UHFFFAOYSA-N
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一般說明
腺嘌呤、胞嘧啶、胸腺嘧啶和鸟嘌呤是核酸DNA和RNA中发现的四种主要核碱基。鸟嘌呤是嘌呤衍生物。据报道，它组装成类似大环的方形平面基团，其中碱基通过氢键相互作用。在DNA和RNA中，据报道，在钠离子或钾离子存在下，一系列鸟嘌呤碱基形成稳定的四链螺旋。已经在各种碳电极的水性介质中研究了鸟嘌呤的电化学氧化。它在生理条件下与过氧亚硝酸盐反应，得到 8-硝基胍。
應用
鸟嘌呤是用于研究鸟嘌呤和腺嘌呤的电化学氧化机理的合适试剂，使用玻碳微电极和循环和微分脉冲伏安法。它可用于制备混合序列肽核酸（PNA）单体。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
A M Oliveira-Brett et al.
Bioelectrochemistry (Amsterdam, Netherlands), 55(1-2), 61-62 (2002-01-12)
The electrochemical oxidation mechanism of guanine and adenine was investigated using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It is pH-dependent and the electron transfer process occurs in consecutive steps with the formation of strongly adsorbed dimers
K Phillips et al.
Journal of molecular biology, 273(1), 171-182 (1997-11-21)
In both DNA and RNA, stretches of guanine bases can form stable four-stranded helices in the presence of sodium or potassium ions. Sequences with a propensity to form guanine tetraplexes have been found in chromosomal telomers, immunoglobulin switch regions, and
Qian Li et al.
The journal of physical chemistry. B, 114(21), 7423-7428 (2010-05-08)
The electrochemical oxidation of guanine is studied in aqueous media at various carbon electrodes. Specifically edge plane pyrolytic graphite (EPPG), basal plane pyrolytic graphite (BPPG), and highly ordered pyrolytic graphite (HOPG) were used, and the voltammetry was found to vary
Synthesis of peptide nucleic acid monomers containing the four natural nucleobases: thymine, cytosine, adenine, and guanine and their oligomerization.
Dueholm KL, et al.
The Journal of Organic Chemistry, 59(19), 5767-5773 (1994)
V Yermilov et al.
Carcinogenesis, 16(9), 2045-2050 (1995-09-01)
Nitric oxide and superoxide anion, both formed in inflamed tissues, react rapidly to form the peroxynitrite anion (ONOO-), a strong oxidant which can initiate reactions characteristic of hydroxyl radical (HO.), nitronium ion (NO2+) and nitrogen dioxide radical (NO2.). Peroxynitrite, therefore
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