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G8377

Sigma-Aldrich

鸟苷 5′-单磷酸 二钠盐 水合物

from yeast, ≥99%

别名:

5′-GMP-Na2, 5′-鸟苷酸 二钠盐 水合物

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About This Item

经验公式（希尔记法）:
C10H12N5Na2O8P · xH2O
CAS号:
5550-12-9
分子量:
407.18 (anhydrous basis)
Beilstein:
3586801
EC號碼:
226-914-1
MDL號碼:
MFCD00151238
分類程式碼代碼:
41106305
PubChem物質ID:
24895338
NACRES:
NA.51

生物源

yeast

品質等級

200

化驗

≥99%

形狀

powder

溶解度

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

儲存溫度

room temp

SMILES 字串

O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H14N5O8P.2Na.H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18);;;1H2/q;2*+1;/p-2/t3-,5-,6-,9-;;;/m1.../s1

InChI 密鑰

MEKWJTZTMVQYSU-CYCLDIHTSA-L

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相关类别

應用

鸟苷5′-一磷酸适用于：
  • 在大气压，以及288.15、293.15和298.15K下测定核苷酸的密度和粘度以及0.0004至0.0014mol/kg溶液中的呋喃糖
  • 检测和验证用于检测产生AMP和GMP的酶的transcreener法
  • 在使用毛细管IC-MS/MS进行核苷酸定量分析过程中制备核苷酸标准品

生化／生理作用

鸟苷5′-单磷酸（GMP）是一种核糖核苷单磷酸，其可在磷酸化成GTP后通过各种RNA聚合酶掺入核糖核酸（RNA）中。 鸟苷-5′-单磷酸（GMP）可用于研究谷氨酸能神经传递的调节过程。

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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Simone Molz et al.
Neurochemical research, 30(1), 83-89 (2005-03-11)
Guanosine-5'-monophosphate (GMP) was evaluated as a neuroprotective agent against the damage induced by glutamate in rat hippocampal slices submitted to glucose deprivation. In slices maintained under physiological conditions, glutamate (0.01 to 10 mM), Kainate, alpha-amino-3-hydroxi-5-methylisoxazole-propionic acid (AMPA), N-methyl-D-aspartate (NMDA), 1S,3R-aminocyclopentane-1,3-dicarboxylic
Hans F N Kvitvang et al.
Journal of chromatography. A, 1370, 70-79 (2014-12-03)
Metabolic profiling has become an important tool in biological research, and the chromatographic separation of metabolites coupled with mass spectrometric detection is the most frequently used approach for such studies. The establishment of robust chromatographic methods for comprehensive coverage of
Emmanuel Ruggiero et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 22(8), 2801-2811 (2016-01-20)
The synthesis and full characterisation (including X-ray diffraction studies and DFT calculations) of two new piano-stool Ru(II) -arene complexes, namely [(η(6) -p-cym)Ru(bpy)(m-CCH-Py)][(PF)6]2 (1) and [(η(6) -p-cym)Ru(bpm)(m-CCH-Py)][(PF)6]2 (2; p-cym=p-cymene, bpy=2,2'-bipyridine, bpm=2,2'-bipyrimidine, and m-CCH-Py=3-ethynylpyridine), is described and discussed. The reaction of the
Simone Molz et al.
Brain research, 1231, 113-120 (2008-07-29)
Glutamate is the main excitatory neurotransmitter in the mammalian nervous system and is essential for its normal functions. However, overstimulation of glutamatergic system due to hyperactivation of NMDA receptors and/or impairment of glutamate reuptake system has been implicated in many
Volumetric and Viscometric Studies of Nucleosides, Nucleotides and Furanose Sugar in Aqueous Medium from 288.15 to 298.15 K.
Singh, M et al.
Iranian Journal of Chemistry and Chemical Engineering, 25, 53-66 (2006)
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