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Merck

SRE0016

Sigma-Aldrich

MATP+

substrate for analysis of acetylcholinesterase (AChE) activity

别名:

1,1-dimethyl-4-acetylthiomethylpiperidinium iodide, acetylcholinesterase substrate, MATP+

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About This Item

经验公式(希尔记法):
C10H20INOS
分子量:
329.24
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.83

product name

MATP+,

儲存溫度

2-8°C

品質等級

SMILES 字串

CC(SCC1CC[N+](C)(C)CC1)=O.[I-]

InChI

1S/C10H20NOS.HI/c1-9(12)13-8-10-4-6-11(2,3)7-5-10;/h10H,4-8H2,1-3H3;1H/q+1;/p-1

InChI 密鑰

WLNVGCIMLLIQAL-UHFFFAOYSA-M

一般說明

1,1-Dimethyl-4-acetylthiomethylpiperidinium iodide (MATP+) is a substrate for analysis of acetylcholinesterase (AChE) activity.  MATP+ is highly selective for specific detection of AChE activity, and thus is advantageous over other AChE substrates like acetylcholine, which can react with multiple enzymes like AChE and also butylcholinesterase (BChE).  Thus with MATP+ in the AChE assay, there is no need to include BChE inhibitors in the protocol.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Nobuo Tsuruoka et al.
PloS one, 7(11), e50824-e50824 (2012-12-05)
Diketopiperazines (DKPs) are naturally-occurring cyclic dipeptides with a small structure and are found in many organisms and in large amounts in some foods and beverages. We found that a chicken essence beverage, which is popular among Southeast Asians as a
Tatsuya Kikuchi et al.
Biological & pharmaceutical bulletin, 33(4), 702-706 (2010-04-23)
The activity of acetylcholinesterase (AChE) is measured to obtain pathological information about the cholinergic system in various disease states and to assess the effect of AChE inhibitors. Using Ellman's method that is commonly used in such examinations, butyrylcholinesterase inhibitors must
Hachiro Sugimoto
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 124(3), 163-170 (2004-08-31)
Enhancement of the activity of cholinergic neurons has been regarded as one of the most promising methods for treating Alzheimer's disease (AD). Donepezil is a representative acetylcholinesterase inhibitor (AChEI) and is a great success among the AChEI drugs. AChEIs are

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