SML1526

依托哌嗪(Eltoprazine) 盐酸盐

≥98% (HPLC)

• 别名: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
• 经验公式（希尔记法）: C₁₂H₁₆N₂O₂ · HCl
• CAS号: 98206-09-8
• 分子量: 256.73
• MDL號碼: MFCD06245586
• 分類程式碼代碼: 12352202
• PubChem物質ID: 329825943
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: H₂O: 10 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: [H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1
• InChI: 1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H
• InChI 密鑰: JFSOSUNPIXJCIX-UHFFFAOYSA-N

说明

一般說明

Eltoprazine, a serotonergic agent, possesses specific anti-aggressive (serenic) properties in various animal models without triggering sedation, motor disturbances, or muscle relaxation.

生化／生理作用

Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H315,H319,H335
• 防範說明: P261 - P264 - P271 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable