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化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to beige
溶解度
DMSO: 20 mg/mL, clear
儲存溫度
−20°C
SMILES 字串
S(Cc2[n](c3c(c(c(c(c3)Br)O)CN(C)C)c2C(=O)OCC)C)c1ccccc1.[Cl-].O.[H+]
InChI
1S/C22H25BrN2O3S.ClH.H2O/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;;/h6-11,26H,5,12-13H2,1-4H3;1H;1H2
InChI 密鑰
PLWQHPWNKPKQJT-UHFFFAOYSA-N
生化/生理作用
盐酸阿比多尔(ARB)是一种小分子单眼用化合物。用于预防流感病毒(IFV)诱导的重症肺炎和病毒相关细胞因子失调。ARB还具有一些免疫调节特性,包括干扰素诱导和巨噬细胞活化的作用。
阿比多尔是一种广谱抗病毒药,已证明对多种包膜和非包膜病毒具有活性,并在临床上用于治疗流感。阿比多尔抑制病毒进入宿主细胞并刺激免疫反应。阿比多尔抑制病毒衣壳与靶细胞的细胞膜之间的融合,从而防止病毒进入。
阿比多尔是一种抗流感抗病毒药。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Yaxin Sun et al.
International journal of clinical pharmacology and therapeutics, 51(5), 423-432 (2013-02-09)
Arbidol is licensed in Russia and China for prophylaxis and treatment of influenza A and B. This study was to assess the pharmacokinetics of single and multiple doses of arbidol in healthy Chinese volunteers. This was a single-center, open-label, two-phase
R A Abramovich et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 57(5-6), 3-6 (2012-11-20)
Rapid analysis of suppositories with ibuprofen and arbidol by quantitative 1H NMR spectroscopy was performed. Optimal conditions for the analysis were developed. The results are useful for design of rapid methods for quality control of suppositories with different components
S Ia Loginova et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 55(7-8), 10-12 (2010-12-15)
The experimental study of the Ingavirin efficacy against the influenza virus A (H5N1) on intranasally-infected albino mice vs. Tamiflue and Arbidol showed that when used for the prophylaxis, urgent prophylaxis and therapy it was effective in the protectiom of the
Pan Deng et al.
Antimicrobial agents and chemotherapy, 57(4), 1743-1755 (2013-01-30)
Arbidol is a broad-spectrum antiviral drug that is used clinically to treat influenza. In this study, the pharmacokinetics, metabolism, and excretion of arbidol were investigated in healthy male Chinese volunteers after a single oral administration of 200 mg of arbidol
I A Leneva et al.
Voprosy virusologii, 55(3), 19-27 (2010-07-09)
The study of the antiviral activity of Russian anti-influenza agents in the cultured MDCK cells demonstrated that arbidol and ribavirin inhibited the reproduction of various influenza A virus strains, including rimantadine- and ozeltamivir-resistant variants, as well as influenza B viruses
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