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Merck
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Key Documents

SML0737

Sigma-Aldrich

MitoTEMPO

≥98% (HPLC), powder, antioxidant

别名:

(2-(2,2,6,6-四甲基哌啶-1-氧基4-亚胺)-2-氧乙基)三苯基氯化磷, Mito-TEMPO

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About This Item

经验公式(希尔记法):
C29H35N2O2P · Cl
分子量:
510.03
分類程式碼代碼:
12352200
NACRES:
NA.77

product name

MitoTEMPO, ≥98% (HPLC)

品質等級

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated
protect from light

顏色

white to light brown

溶解度

H2O: 10 mg/mL, clear

儲存溫度

−20°C

應用

MitoTEMPO已被用作线粒体靶向抗氧化剂。

生化/生理作用

MitoTEMPO是一种线粒体靶向抗氧化剂,一种线粒体超氧化物的特异清除剂。 MitoTEMPO是抗氧化剂哌啶硝基氧TEMPO与亲脂阳离子三苯基鏻的组合,使MitoTEMPO能够轻松通过脂质双层膜,并在线粒体中积累数百倍。 线粒体功能障碍和氧化应激可导致多种疾病,包括心血管、肾脏、肝脏疾病、帕金森′s病和阿尔茨海默′s病。

其他說明

光敏性

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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