SML0418

ML-161

≥98% (HPLC)

• 别名: 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]-benzamide
• 经验公式（希尔记法）: C₁₇H₁₇BrN₂O₂
• CAS号: 423735-93-7
• 分子量: 361.23
• MDL號碼: MFCD03063772
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825413
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 5 mg/mL (clear solution)
• 儲存溫度: 2-8°C
• SMILES 字串: CCCC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1
• InChI: 1S/C17H17BrN2O2/c1-2-6-16(21)19-12-7-5-8-13(11-12)20-17(22)14-9-3-4-10-15(14)18/h3-5,7-11H,2,6H2,1H3,(H,19,21)(H,20,22)
• InChI 密鑰: DFOVLSMXPWPCFH-UHFFFAOYSA-N

说明

生化／生理作用

ML-161 is an antagonist of the protease-activated receptor 1 (PAR1), that inhibits thrombin and SFLLN-induced platelet activation. ML-161 dose dependently inhibits SFLLN-induced expression of P-selectin with an IC₅₀ of 0.26 μM.

安全信息

• 象形圖: GHS09
• 訊號詞: Warning
• 危險聲明: H410
• 防範說明: P273 - P391 - P501
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable