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Merck
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Key Documents

SCP0187

Sigma-Aldrich

Gastrin I, Mini human

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About This Item

经验公式（希尔记法）:
C74H99N15O26S1
分子量:
1646.73
分類程式碼代碼:
51111800
NACRES:
NA.32

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥75%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2

應用

Gastrin is a linear polypeptide that induces the secretion of gastric acid (HCl) by parietal cells. Gastrin is found in three major forms: gastrin-34 (big gastrin); gastrin-17 (little gastrin) and gastrin-13 minigastrin.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Incretin physiology beyond glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: cholecystokinin and gastrin peptides.
Rehfeld JF.
Current Opinion in Gastroenterology, 201, 405-411 (2011)
Mitchell L Schubert
Current opinion in gastroenterology, 27(6), 536-542 (2011-09-08)
The review summarizes the past year's literature regarding the regulation of gastric exocrine and endocrine secretion, both basic science and clinical. Gastric acid secretion is an elaborate and dynamic process that is regulated by neural (efferent and afferent), hormonal (e.g.
Sara Calatayud et al.
Mini reviews in medicinal chemistry, 10(1), 8-19 (2010-04-13)
Gastrin release is affected by gastric inflammatory conditions. Antral G cells respond to inflammatory mediators by increasing gastrin secretion. Accumulating experimental evidence suggests that gastrin exerts immunomodulatory and proinflammatory effects. Gastrin could be a contributing factor to these pathologies, which
Gastrin in gastrointestinal diseases.
Daniel Fourmy et al.
Gastroenterology, 141(3), 814-818 (2011-07-20)
Suzana Kovac et al.
Biochimica et biophysica acta, 1813(5), 889-895 (2011-02-16)
The peptide hormone gastrin has been identified as a major regulator of acid secretion and a potent mitogen for normal and malignant gastrointestinal cells. The importance of gastric acid in the absorption of dietary iron first became evident 50 years

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