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Key Documents

SAB5900402

Sigma-Aldrich

Anti-Monkeypox virus/MPXV M1R Antibody (SAA0283)

new

别名:

M1R, Monkeypox virus (MPXV)

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About This Item

分類程式碼代碼:
51111800

生物源

mouse

品質等級

重組細胞

expressed in CHO cells

共軛

unconjugated

抗體表格

affinity purified immunoglobulin

無性繁殖

SAA0283, recombinant monoclonal

化驗

>95% (SDS-PAGE)

形狀

liquid

分子量

150 kDa

物種活性

monkeypox virus

濃度

1 mg/mL

技術

ELISA: 1:2000-1:2000
neutralization: 0.01-10 μg/mL

顏色

colorless

pH值

7.4

同型

IgG2a, kappa

Protein ID登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

-65 to -96°C

目標翻譯後修改

unmodified

一般說明

Anti-Monkeypox virus/MPXV M1R Antibody, clone SAA0283, is a recombinant monoclonal antibody composed of two heavy chains and two light chains. It is a type of immunoglobulin G (IgG) antibody, which is the most common type of antibody found in the blood and other bodily fluids of humans and other mammals.


Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.

特異性

Monoclonal Anti-Monkeypox virus/MPXV M1R Antibody, clone SAA0283 is specific to the monkeypox virus and binds to its surface proteins. This binding blocks the virus from entering cells and prevents it from replicating, thus preventing infection.

應用

ELISA,neutralization

包裝

100µg per vial / 1 mg per vial

儲存和穩定性

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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