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生物源
mouse
品質等級
重組細胞
expressed in CHO cells
共軛
unconjugated
抗體表格
affinity purified immunoglobulin
無性繁殖
SAA0282, recombinant monoclonal
化驗
>95% (SDS-PAGE)
形狀
liquid
分子量
150 kDa
物種活性
monkeypox virus
濃度
1 mg/mL
技術
ELISA: 1:2000-1:4000
neutralization: 0.01-10 μg/mL
顏色
colorless
pH值
7.4
同型
IgG2a, kappa
Protein ID登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
-65 to -96°C
目標翻譯後修改
unmodified
一般說明
Anti-Monkeypox virus/MPXV H3L Antibody, clone SAA0282 is produced in mouse. The monoclonal antibodies are IgG immunoglobulins, which consist of two heavy chains and two light chains. Each heavy chain contains four domains, and each light chain contains two domains. The antibody binds to the antigen of the monkeypox virus, which is the H3L protein.
Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.
Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.
特異性
Monoclonal Anti-Monkeypox virus/MPXV H3L Antibody, clone SAA0282 is highly specific and bind to the H3L protein of the virus. This binding inhibits the virus from entering cells, thus preventing infection. The antibodies also trigger the body’s immune system to produce anti-viral proteins that can clear the virus from the body.
應用
ELISA,neutralization
包裝
100µg per vial / 1 mg per vial
儲存和穩定性
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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