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Merck
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主要文件

SAB5702582

Sigma-Aldrich

Anti-Renin Antibody, clone 1L1B7, Rabbit Monoclonal

别名:

HNFJ2

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46
無性繁殖:
1L1B7, monoclonal
application:
WB
物種活性:
human
技術:
western blot: 1:500 - 1:2000
citations:

生物源

rabbit

品質等級

材料

colorless

無性繁殖

1L1B7, monoclonal

形狀

liquid

分子量

50 kDa

物種活性

human

濃度

0.68 mg/mL

技術

western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFK

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... REN(5972)

一般說明

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Renin (P00797).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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