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Merck
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Key Documents

SAB5702262

Sigma-Aldrich

Anti-MMP7 Antibody, clone 9D8S10, Rabbit Monoclonal

别名:

MMP7,MMP-7,MPSL1,PUMP-1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

9D8S10, monoclonal

形狀

liquid

物種活性

human, rat, rat

濃度

4.84 mg/mL

技術

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MMP7(4316)

一般說明

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.

免疫原

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of human MMP7.

應用

WB, IHC

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Aquatic Chronic 2 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3


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