推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 29 kDa
物種活性
human, mouse, rat
濃度
~1 mg/mL
技術
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... MMP7(4316)
一般說明
Anti-MMP-7 Antibody detects endogenous levels of total MMP-7 protein.
Matrix metalloproteinase-7 (MMP7) is also termed as matrilysin. It is located on human chromosome 11q21-->q22. It belongs to the MMP enzyme family and is highly expressed in cancer cells. MMP7 is exclusively released by epithelial cells.
免疫原
The antiserum was produced against synthesized peptide derived from human MMP-7.
Immunogen Range: 218-267
Immunogen Range: 218-267
應用
Anti-MMP-7, C-Terminal antibody has been used in immunofluorescence.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunofluorescence (1 paper)
生化／生理作用
Overexpression of matrix metalloproteinase-7 (MMP7) is observed in various cancers, such as breast, lung, prostate, esophagus, stomach, endometrium, and ovarian carcinomas, as well as esophageal squamous cell carcinomas. Activated MMP7 plays a vital role in human colorectal cancer (CRC) liver metastases. It is essential for the development of tumor in the absence of PKP3 (plakophilin3).
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney
Oelusarz A, et al.
Physiological Reports, 1(5) (2013)
Mapping of the metalloproteinase gene matrilysin (MMP7) to human chromosome 11q21-->q22.
Knox JD
Cytogenetics and Cell Genetics, 72(2-3), 179-182 (1996)
Anna Oelusarz et al.
Physiological reports, 1(5) (2013-11-26)
The percentage of the U.S. population over 65 is rapidly increasing, as is the incidence of chronic kidney disease (CKD). The kidney is susceptible to age-dependent alterations in structure, specifically tubulointerstitial fibrosis, that lead to CKD. Matrix metalloproteinases (MMPs) were
Matrix metalloproteinase-7 expression in colorectal cancer liver metastases: evidence for involvement of MMP-7 activation in human cancer metastases.
Zeng ZS
Clinical Cancer Research, 8(1), 144-148 (2002)
Srikanta Basu et al.
PloS one, 10(4), e0123979-e0123979 (2015-04-16)
Plakophilin3 (PKP3) loss results in increased transformation in multiple cell lines in vitro and increased tumor formation in vivo. A microarray analysis performed in the PKP3 knockdown clones, identified an inflammation associated gene signature in cell lines derived from stratified
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持