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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 13 pg/mL
standard curve range: 12.29-3000 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... IL36G(56300)
一般說明
The IL36G ELISA kit provides for the Quantitative measurement of IL-36 gamma in Cell Culture Supernatants, Plasma and Serum.
Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types.
Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types.
應用
请参考Protocol了解详情。
生化／生理作用
Members of interleukin (IL)-1 family of cytokines play a vital role in regulating immune responses to infectious challenges and sterile insults. IL-36 is implicated in mucosal immunity, such as lung anti-bacterial responses. Interleukin-36 γ (IL36G) participates in inflammation response and differentiation. Overexpression of IL36G has been observed in psoriasis patients. Thus, down regulation IL36G can be considered as an effective method to treat psoriasis.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Participation of interleukin family 1 in the development of inflammatory reaction in the infectious process. 1. General characteristics of the interleukin family 1.
Abaturov AE, et al.
CHILDS HEALTH (2014)
IL-36γ inhibits differentiation and induces inflammation of keratinocyte via Wnt signaling pathway in psoriasis.
Wang W, et al.
International Journal of Medical Sciences, 14(10), 1002-1002 (2017)
IL-1 family cytokines in cardiovascular disease.
Pfeiler S, et al.
Cytokine (2017)
IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and-negative bacterial pneumonia.
Kovach MA, et al.
Mucosal Immunology, 10(5), 1320-1320 (2017)
Jennifer Mildenberger et al.
Autophagy, 13(10), 1664-1678 (2017-08-19)
Inflammation is crucial in the defense against infections but must be tightly controlled to limit detrimental hyperactivation. Our diet influences inflammatory processes and omega-3 polyunsaturated fatty acids (n-3 PUFAs) have known anti-inflammatory effects. The balance of pro- and anti-inflammatory processes
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