PZ0223

PF-04991532

≥98% (HPLC)

• 别名: 6-[[(2S)-3-Cyclopentyl-1-oxo-2-[4-(trifluoromethyl)-1H-imidazol-1-yl]propyl]amino]-3-pyridinecarboxylic acid, PF 04991532
• 经验公式（希尔记法）: C₁₈H₁₉F₃N₄O₃
• CAS号: 1215197-37-7
• 分子量: 396.36
• 分類程式碼代碼: 51111800
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: FC(F)(F)c1nc[n](c1)[C@@H](CC3CCCC3)C(=O)Nc2ncc(cc2)C(=O)O
• InChI: 1S/C18H19F3N4O3/c19-18(20,21)14-9-25(10-23-14)13(7-11-3-1-2-4-11)16(26)24-15-6-5-12(8-22-15)17(27)28/h5-6,8-11,13H,1-4,7H2,(H,27,28)(H,22,24,26)/t13-/m0/s1
• InChI 密鑰: GKMLFBRLRVQVJO-ZDUSSCGKSA-N

说明

生化／生理作用

PF-04991532 is a potent and hepatoselective glucokinase activator that reduces mean daily glucose (MDG), fasting plasma glucose (FPG) and glucose excursion in humans.

PF-04991532 is a potent and hepatoselective glucokinase activator.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable