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Artur Schmidtchen et al.
The Journal of biological chemistry, 284(26), 17584-17594 (2009-04-29)
A novel approach for boosting antimicrobial peptides through end tagging with hydrophobic oligopeptide stretches is demonstrated. Focusing on two peptides derived from kininogen, GKHKNKGKKNGKHNGWK (GKH17) and HKHGHGHGKHKNKGKKN (HKH17), tagging resulted in enhanced killing of Gram-positive Staphylococcus aureus, Gram-negative Escherichia coli
Eri Nakayama et al.
The Journal of infectious diseases, 204 Suppl 3, S978-S985 (2011-10-19)
Marburg virus (MARV) and Ebola virus (EBOV) cause severe hemorrhagic fever in primates. Earlier studies demonstrated that antibodies to particular epitopes on the glycoprotein (GP) of EBOV enhanced virus infectivity in vitro. To investigate this antibody-dependent enhancement (ADE) in MARV
Linn S Strandberg et al.
PloS one, 8(9), e72668-e72668 (2013-09-17)
Congenital heart block (CHB) is a transplacentally acquired autoimmune disease associated with anti-Ro/SSA and anti-La/SSB maternal autoantibodies and is characterized primarily by atrioventricular (AV) block of the fetal heart. This study aims to investigate whether the T-type calcium channel subunit
Mukesh Pasupuleti et al.
The Journal of biological chemistry, 282(4), 2520-2528 (2006-11-30)
The human anaphylatoxin peptide C3a, generated during complement activation, exerts antimicrobial effects. Phylogenetic analysis, sequence analyses, and structural modeling studies paired with antimicrobial assays of peptides from known C3a sequences showed that, in particular in vertebrate C3a, crucial structural determinants
Maximillian Rosario et al.
Journal of virology, 84(12), 5898-5908 (2010-04-09)
Mycobacterium bovis bacillus Calmette-Guérin (BCG), which elicits a degree of protective immunity against tuberculosis, is the most widely used vaccine in the world. Due to its persistence and immunogenicity, BCG has been proposed as a vector for vaccines against other
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