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Merck

P7936

Sigma-Aldrich

磷酸肌酸 二钠盐 水合物

≥97%

别名:

N-(亚氨基[膦氨基]甲基)-N-甲基甘氨酸

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About This Item

线性分子式:
C4H8N3O5PNa2 · x H2O
CAS号:
分子量:
255.08 (anhydrous basis)
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

磷酸肌酸 二钠盐 水合物, ≥97%

品質等級

化驗

≥97%

形狀

powder

雜質

≤0.02% free creatine

顏色

white

溶解度

water: 50 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

O.[Na+].[Na+].CN(CC(O)=O)C(=N)NP([O-])([O-])=O

InChI

1S/C4H10N3O5P.2Na.H2O/c1-7(2-3(8)9)4(5)6-13(10,11)12;;;/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);;;1H2/q;2*+1;/p-2

InChI 密鑰

KZVYPOKBYRXZKS-UHFFFAOYSA-L

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應用

磷酸肌酸二钠盐水合物已用于:
  • 作为爪蟾缓冲液(XB)组分,用于去除膜吸附性蛋白质
  • 作为M5+缓冲液组分,进行极化全内反射荧光(polTIRF)实验
  • 作为ATP再生系统组分,用于7-硝基-2-1,3-苯并噁二唑-4-基磷脂(NBD-PL)转位检测

生化/生理作用

磷酸肌酸(Phosphocreatine)因其在肌酸激酶作用下的最快再生形式而广为人知,起到临时能量缓冲器的作用。磷酸肌酸存在于肌肉组织中,在维持肌肉细胞的能量稳态中起重要作用。
磷酸肌酸二钠盐水合物可用于研究鼻咽癌细胞和诱发的暂时性心脏骤停。它也用于评估伏隔核中腺苷A(2A)受体调节对大鼠可卡因寻求行为的影响。
磷酸肌酸是脊椎动物和某些无脊椎动物肌肉的高能磷酸基储蓄池,提供ADP-ATP转换所需磷酸。

準備報告

酶法制备。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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