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化驗
~98% (TLC)
形狀
powder
溶解度
chloroform: 20 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
O=C(CCCCCCC/C=C\CCCCCCCC)NCCO
InChI
1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
InChI 密鑰
BOWVQLFMWHZBEF-KTKRTIGZSA-N
基因資訊
human ... CNR1(1268) , CNR2(1269) , PPARA(5465) , TRPV1(7442)
mouse ... Cnr2(12802)
rat ... Cnr1(25248)
一般說明
油酰乙醇胺(OEA)是一种内源性脂肪酸乙醇胺。小肠细胞、脂肪组织、神经元和星形胶质细胞可产生OEA。
應用
N-油酰乙醇胺已用于研究其对胰高血糖素样肽(GLP)-1RA介导的厌食信号传导和体重减轻的影响。
生化/生理作用
油酰乙醇胺(OEA)是一种脂质介体,有助于控制各种生物功能,例如食物摄取。它调节小肠中的基因表达。OEA能够引发产生多种受体,例如1型大麻素受体(CB1)、过氧化物酶体增殖物激活受体(PPAR)和G蛋白偶联受体119(GPR119)。
过氧化物酶体增殖物激活受体α (PPARα )激动剂
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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