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Merck

N3877

Sigma-Aldrich

4-硝基苯硫酸钾

sulfatase substrate, chromogenic, ≥98% (TLC), powder

别名:

4-硝基苯硫酸盐 钾盐

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About This Item

线性分子式:
NO2C6H4OSO2OK
CAS号:
分子量:
257.26
Beilstein:
3786392
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

4-硝基苯硫酸钾, sulfatase substrate

化驗

≥98% (TLC)

形狀

powder

mp

246-250 °C (lit.)

溶解度

water: 50 mg/mL, clear, colorless to very faintly greenish-yellow (to Very Light Yellow)

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

[K+].[O-][N+](=O)c1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C6H5NO6S.K/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;/h1-4H,(H,10,11,12);/q;+1/p-1

InChI 密鑰

BITVAZYUWRLLCN-UHFFFAOYSA-M

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應用

4-硝基苯基硫酸钾已用于:
  • 作为底物,测定无细胞体腔液中芳基硫酸酯酶的活性
  • 作为基于p-硝基苯基糖苷的酶分析的底物
  • ,抑制芳基硫酸酯酶
  • 作为有机芳基酯硫酸酯的无机类似物

基底

显色硫酸酯酶底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Maternal and neonatal urinary excretion of sulfate and glucuronide ritodrine conjugates
Brashear WT, et al.
Clinical Pharmacology and Therapeutics, 44(6), 634-641 (1988)
Elif Akin Kazancioğlu et al.
Journal of enzyme inhibition and medicinal chemistry, 27(6), 880-885 (2011-12-08)
The possible sulfatase activity of several carbonic anhydrase (CA, EC 4.2.1.1) isoforms have been investigated with a series of synthesized methanesulfonate derivatives of phenols. Four α-CA isozymes, i.e. hCA I, hCA II, hCA IV and hCA VI (h = human
Shina Caroline Lynn Kamerlin
The Journal of organic chemistry, 76(22), 9228-9238 (2011-10-11)
Both phosphoryl and sulfuryl transfers are ubiquitous in biology, being involved in a wide range of processes, ranging from cell division to apoptosis. Additionally, it is becoming increasingly clear that enzymes that can catalyze phosphoryl transfer can often cross-catalyze sulfuryl
M D Burkart et al.
Analytical biochemistry, 274(1), 131-137 (1999-10-21)
We have developed a continuous spectrophotometric coupled-enzyme assay for sulfotransferase activity. This assay is based on the regeneration of 3'-phosphoadenosine-5'-phosphosulfate (PAPS) from the desulfated 3'-phosphoadenosine-5'-phosphate (PAP) by a recombinant aryl sulfotransferase using p-nitrophenyl sulfate as the sulfate donor and visible
E S Lin et al.
Biochemical and biophysical research communications, 271(3), 818-822 (2000-05-18)
The sulfation of a nucleotide is an indispensable step for the sulfuryl group transfer in a biological system. The product and cosubstrate of sulfotransferase in physiological condition are adenosine 3',5'-bisphosphate (PAP) and 3'-phospho adenosine 5'-phosphosulfate (PAPS), respectively. We find that

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