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Merck

M7523

Sigma-Aldrich

Anti-Myosin (Skeletal) antibody produced in rabbit

enhanced validation

whole antiserum

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

whole antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

包含

15 mM sodium azide

物種活性

human

加強驗證

independent
Learn more about Antibody Enhanced Validation

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20 using human or animal skeletal muscle
indirect immunofluorescence: 1:20 using human or animal sletetal muscle

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

一般說明

Myosin is a 480,000 dalton protein containing two identical heavy chains (200,000 daltons each) and four light chains (15,000-26,000 daltons). Myosin molecules consist of two major regions: tails (rods) and heads; they aggregate into filaments through the tail region. Multiple forms of myosin heavy chains exist for each muscle type; skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle.

特異性

Specifically labels the A bands of human and animal skeletal muscle. Does not stain human smooth muscle tissue.

免疫原

whole myosin (heavy and light chains) from human skeletal muscle.

應用

Anti-Myosin (Skeletal) antibody produced in rabbit has been used in:
  • immunohistochemistry
  • immunostaining
  • western blotting
  • immunofluorescence
  • immunolocalization
  • immunocytochemistry

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Western Blotting (1 paper)

品質

The antiserum has been treated to remove lipoproteins.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Xenotransplantation of human dental pulp stem cells in xn-plateletrich-009f plasma for the treatment of xn-fullthickness-sm6g articular cartilage defects in a rabbit model
Yanasse RH, et al.
Experimental and Therapeutic Medicine, 17(6), 4344-4356 (2019)
Hilda Merino et al.
Oxidative medicine and cellular longevity, 2018, 6043064-6043064 (2018-08-29)
Doxorubicin (Dox) is a potent chemotherapeutic drug known for its dose-dependent and serious adverse effects, such as cardiotoxicity and myotoxicity. Dox-induced cardiotoxicity (DIC) and muscle toxicity (DIMT) have been studied; however, the mechanisms of Dox-induced apoptosis in soleus muscle are
Tatiana Jazedje et al.
Journal of translational medicine, 7, 46-46 (2009-06-23)
The possibility of using stem cells for regenerative medicine has opened a new field of investigation. The search for sources to obtain multipotent stem cells from discarded tissues or through non-invasive procedures is of great interest. It has been shown
Mariane Secco et al.
Stem cells (Dayton, Ohio), 26(1), 146-150 (2007-10-13)
The identification of mesenchymal stem cell (MSC) sources that are easily obtainable is of utmost importance. Several studies have shown that MSCs could be isolated from umbilical cord (UC) units. However, the presence of MSCs in umbilical cord blood (UCB)
Multipotent Stem Cells from Umbilical Cord: Cord Is Richer than Blood!
Secco M, et al.
Stem Cells, 26(1), 146-150 (2008)

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