L2774

林可霉素 盐酸盐

suitable for cell culture, BioReagent

• 别名: Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside 盐酸盐, 林可霉素 盐酸盐
• 经验公式（希尔记法）: C₁₈H₃₄N₂O₆S · HCl
• CAS号: 859-18-7
• 分子量: 443.00
• Beilstein: 4171650
• EC號碼: 212-726-7
• MDL號碼: MFCD00083647
• 分類程式碼代碼: 12352207
• PubChem物質ID: 329817401
• NACRES: NA.76

属性

• product name: 林可霉素 盐酸盐, BioReagent, suitable for cell culture
• 產品線: BioReagent
• 品質等級: 200
• 效力: 800-900 units per mg
• 技術: cell culture | mammalian: suitable
• 顏色: white to yellow-white
• 溶解度: H₂O: 4 mL, clear, colorless to faintly yellow (200 mg + 4 mL H2O)
• 抗生素活性譜: Gram-positive bacteria
• 作用方式: protein synthesis | interferes
• 儲存溫度: 2-8°C
• SMILES 字串: Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
• InChI: 1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1
• InChI 密鑰: POUMFISTNHIPTI-BOMBIWCESA-N

说明

一般說明

Chemical structure: macrolide

應用

Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It is produced by Streptomyces lincolnensis var. lincolnensis, and has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.

生化／生理作用

作用方式：林可霉素可通过在23S rRNA的肽基转移酶环区域内形成交联来抑制细菌蛋白质的合成。†

抗菌谱：盐酸林可霉素对革兰氏阳性菌有效。

準備報告

This product is soluble in water at 50 mg/mL, yielding a clear, colorless solution.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves