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Merck
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K4894

Sigma-Aldrich

Kolliphor HS 188

solid

别名:

聚（乙二醇）- 嵌段 - 聚（丙二醇）- 嵌段 - 聚（乙二醇）, Lutrol F68, Poloxamer 188

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About This Item

CAS号:
9003-11-6
MDL號碼:
MFCD00082049
分類程式碼代碼:
12161902
NACRES:
NA.75

agency

USP/NF
meets USP testing specifications

品質等級

300

形狀

solid

分子量

8.400 g/mol

pH值

5.0-7.5(2.5% solution)

應用

sample preservation

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI 密鑰

RVGRUAULSDPKGF-UHFFFAOYSA-N

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相关类别

一般說明

Poloxamer 188是一种非离子型两亲共聚物，其中心链为疏水聚氧丙烯，末端为亲水聚氧乙烯。

應用

Poloxamer 188已用作细胞解离/最小基本介质（MEM）的组分，以使用 EpCAM 抗体偶联磁珠分选肿瘤细胞。
Poloxamer 188已被用作F17培养基中的补充剂，用于培养HEK293-6E细胞。它还被用作流式细胞分析(FACS)缓冲液的组分，用作保护细胞免受流体动力损害的非离子型除垢剂。

生化／生理作用

Poloxamer 188具有细胞保护、血液流变学、抗炎、抗血栓活性。它可以维持膜屏障功能的稳定。P188 可降低表面张力和疏水细胞粘附。它还能抑制受 Fe2+ 和 H2O2 刺激的脂质过氧化。

法律資訊

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

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