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Merck

K1751

Sigma-Aldrich

酮洛芬

≥98% (TLC)

别名:

2-(3-苯甲酰苯基)丙酸

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About This Item

经验公式(希尔记法):
C16H14O3
CAS号:
分子量:
254.28
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic

品質等級

化驗

≥98% (TLC)

形狀

powder

溶解度

ethanol: 50 mg/mL, clear, colorless to yellow

起源

Bayer

SMILES 字串

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI 密鑰

DKYWVDODHFEZIM-UHFFFAOYSA-N

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一般說明

酮洛芬属于2-芳基丙酸类化合物。

應用

酮洛芬已被用于:
  • 作为检测样品,通过色谱和显微技术分析长储存期的影响
  • 作为非选择性COX抑制剂,在大鼠皮下注射,研究其对应激/盐酸甲基苯丙胺诱导的闭合蛋白、紧密连接蛋白-5和COX-2蛋白免疫反应性、β-营养不良聚糖的截短、脑水含量、以及异硫氰酸荧光素-葡聚糖外渗的变化的影响
  • 在磷酸盐缓冲液中研究其抑制热诱导白蛋白变性的能力

生化/生理作用

它可作为治疗强直性脊柱炎、类风湿性关节炎和骨关节炎的有效药物。 它还具有解热和镇痛作用。酮洛芬可防止前列腺素合成酶的作用。
非甾体类抗炎化合物,具有COX-1选择性。

特點和優勢

该化合物由Bayer开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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Chromatograms

application for HPLCapplication for HPLCapplication for HPLC

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