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生物源
mouse
品質等級
重組細胞
expressed in E. coli
化驗
≥97% (SDS-PAGE)
形狀
lyophilized powder
效力
0.02-0.2 ng/mL EC50
品質
endotoxin tested
分子量
~21.7 kDa
包裝
pkg of 5 and 25 μg
技術
cell culture | mammalian: suitable
雜質
≤1.0EU/mg
顏色
white
UniProt登錄號
儲存溫度
−20°C
基因資訊
mouse ... Il6(16193)
相关类别
生化／生理作用
白细胞介素-6 (IL-6) 是最初在双链 RNA 刺激的细胞培养基中发现的一种多功能蛋白。IL-6 似乎直接参与了感染和损伤后发生的反应，并可能证明在调节急性期反应方面与 IL-1 和 TNF-α同样重要。据报道，IL-6 由成纤维细胞、活化的 T 细胞、活化的单核细胞或巨噬细胞以及内皮细胞产生。作用于多种细胞，包括成纤维细胞、髓系祖细胞、T 细胞、B 细胞和肝细胞。如许多同义词所示，IL-6 诱导多种效应：浆细胞瘤生长因子 (PCT-GF)、干扰素-β-2（IFN-β 2 ）、单核细胞来源的人 B 细胞生长因子、B 细胞刺激因子 (BSF-2)、肝细胞刺激因子 (HSF)、白细胞介素杂交瘤/浆细胞瘤-1 (IL-HP1)。此外，IL-6 似乎在 T 淋巴细胞增殖中与 IL-2 相互作用。IL-6 还可增强 IL-3 对多潜能造血祖细胞的增殖作用。
外觀
从不含添加剂的无菌过滤溶液中冻干。
分析報告
重组小鼠IL-6的生物学活性已通过使用T1165.85.2.1细胞经过细胞增殖试验进行测定。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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