推荐产品
生物源
synthetic (organic)
化驗
≥95%
形狀
powder
顏色
yellow
mp
130 °C
溶解度
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL
methanol: 10 mg/mL
DMSO: 12 mg/mL
chloroform: 20 mg/mL
儲存溫度
−20°C
SMILES 字串
O=S(OC1=CC=C(C[C@@H](C(N2CCN(C3=CC=CC=C3)CC2)=O)N(C)S(C4=CC=CC5=C4C=CN=C5)(=O)=O)C=C1)(C6=CC=CC7=C6C=CN=C7)=O
InChI
1S/C38H35N5O6S2/c1-41(50(45,46)36-11-5-7-29-26-39-19-17-33(29)36)35(38(44)43-23-21-42(22-24-43)31-9-3-2-4-10-31)25-28-13-15-32(16-14-28)49-51(47,48)37-12-6-8-30-27-40-20-18-34(30)37/h2-20,26-27,35H,21-25H2,1H3/t35-/m0/s1
InChI 密鑰
RJVLFQBBRSMWHX-DHUJRADRSA-N
基因資訊
human ... P2RX7(5027)
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生化/生理作用
选择性抑制大鼠脑 Ca2+/钙调蛋白依赖性蛋白激酶 II。
特點和優勢
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Biochimica et biophysica acta, 1798(11), 2058-2066 (2010-07-31)
The P2X7 receptor is an extracellular ATP-gated cation channel critical in inflammation and immunity, and can be up-regulated by IFN-γ and LPS. This study aimed to examine the effect of TGF-β1 on the up-regulation of P2X7 function and expression in
Antagonists of the P2X(7) receptor. From lead identification to drug development.
Journal of medicinal chemistry, 52(10), 3123-3141 (2009-02-05)
Stem cell research, 23, 39-49 (2017-07-04)
New methods are needed to reduce dynamic blebbing which inhibits cell attachment and survival during passaging of pluripotent stem cells. We tested the hypothesis that activation of the P2X7 receptor by extracellular ATP during passaging initiates dynamic blebbing. The P2X7
Science immunology, 3(30) (2018-12-16)
Tissue-resident memory T cells (TRM) are noncirculating immune cells that contribute to the first line of local defense against reinfections. Their location at hotspots of pathogen encounter frequently exposes TRM to tissue damage. This history of danger-signal exposure is an
The Journal of membrane biology, 172(1), 59-66 (1999-11-07)
To assess the activation of the charybdotoxin-insensitive K(+) channel responsible for Regulatory Volume Decrease (RVD) after substantial volume increases, we measured intracellular pH (pH(i)), intracellular calcium ([Ca(2+)](i)) and inhibitors of kinases and phosphoprotein phosphatases in guinea pig jejunal villus enterocytes
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