H8892

Heparin disaccharide I-H sodium salt

• 别名: α-ΔUA-2S-[1→4]-GlcN-6S
• 线性分子式: C₁₂H₁₇NO₁₆S₂Na₂
• CAS号: 136098-04-9
• 分子量: 541.37
• MDL號碼: MFCD00466926
• 分類程式碼代碼: 12352201
• PubChem物質ID: 329815254
• NACRES: NA.25

属性

• 化驗: ~99% (HPLC)
• 形狀: solid
• 技術: HPLC: suitable
• 顏色: white to faint yellow
• 儲存溫度: −20°C
• SMILES 字串: [Na+].[Na+].[Na+].N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O[C@@H]2OC(=C[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@@H]1O
• InChI: 1S/C12H19NO16S2.3Na/c13-6-7(15)9(5(26-11(6)18)2-25-30(19,20)21)28-12-8(29-31(22,23)24)3(14)1-4(27-12)10(16)17;;;/h1,3,5-9,11-12,14-15,18H,2,13H2,(H,16,17)(H,19,20,21)(H,22,23,24);;;/q;3*+1/p-3/t3-,5+,6+,7+,8+,9+,11?,12-;;;/m0.../s1
• InChI 密鑰: WHYGSGRAJJCXLY-LXROVJCJSA-K

说明

應用

Heparin disaccharide I-H sodium salt has been used as a non-naphthalene, negatively charged, bivalent compound to test its ability to induce liquid-liquid phase separation (LLPS).

生化／生理作用

Heparin disaccharide is a bivalent compound with less hydrophobic nature. It elevates the cytosolic calcium (Ca²⁺) extrusion rate and may serve as a potential drug for the activation of Na+ /Ca²⁺ exchanger (NCX).

Products of the digestion of heparin and heparan sulfate by various heparinases

其他說明

In the following listings, ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GlcN = D-glucosamine; Ac = Acetyl; NS, 2S, 6S, = N-sulfo, 2-sulfate and 6-sulfate respectively.

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)