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Merck
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主要文件

H2667

Sigma-Aldrich

Histone H4 human

别名:

Histone, Human

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.25

生物源

human

品質等級

重組細胞

expressed in E. coli

形狀

liquid

濃度

1 mg/mL

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... H4C1(121504)

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一般說明

Histones are highly basic chromatin proteins. They tightly pack and organize eukaryotic DNA into nucleosomes. Nucleosomes consist of a histone octamer made of a tetramer of histones H3 and H4 with two dimers of histones H2A and H2B, wherein the 147 DNA base pairs are wrapped around this histone complex.

應用

Histone H4 human has been used in far-western blot analysis for protein identification. It has also been used in the preparation of standard protein solution for protein digestion.

生化/生理作用

Histones regulate transcription, DNA replication, DNA repair, and recombination.

其他說明

Supplied as 1 mg/mL in 20 mM NaPO4, pH 7.0, 0.3 M NaCl, 1 mM EDTA

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Khoa N Pham et al.
The journal of physical chemistry. B, 125(19), 4977-4986 (2021-05-12)
Histones are highly basic chromatin proteins that tightly package and order eukaryotic DNA into nucleosomes. While the atomic structure of the nucleosomes has been determined, the three-dimensional structure of DNA-free histones remains unresolved. Here, we combine tandem nonlinear and linear
Apurva Bhardwaj et al.
International journal of molecular sciences, 22(1) (2021-01-07)
Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) is an essential protein that regulates cellular processes such as cell proliferation, apoptosis, and differentiation. It is known to bind with several proteins to carry out various cellular functions. In this study, we

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