跳转至内容
Merck
所有图片(1)

Key Documents

GERPN6302

碘代乙酰胺

Cytiva RPN6302, pack of 25 g

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352202
NACRES:
NA.77

形狀

solid

特點

wetted part: no

包裝

pack of 25 g

製造商/商標名

Cytiva RPN6302

顏色

Yellowish

溶解度

cold water: soluble (Easily soluble in cold and hot water)

儲存溫度

2-8°C

一般說明

Used for the efficient alkylation of thiols while minimizing oxidation of competing thiol pairs in protein samples.

應用

Iodoacetamide has been used:
  • as a component in urea-sodium dodecyl sulfate (SDS) buffer for yeast cell lysis in immunoprecipitation assay
  • in equilibration of pH gradient strips during the second dimension run in isoelectric focusing
  • as a protein alkylation agent

生化/生理作用

Iodoacetamide (IAA) modifies thiol groups in proteins by S-carboxyamidomethylation. Iodoacetamide is an alkylating agent. IAA is commonly used to analyze the key role of cysteine residues in the catalytic reactions of enzymes. It is also used in the derivatization of cysteine residues in proteins for proteomic analysis. IAA irreversibly inhibits glyceraldehyde-3-phosphate dehydrogenase (GAPDH).

特點和優勢

  • Ultrapure, proteomic-grade iodoacetamide is used for efficient alkylation of thiols while minimizing oxidation of the competing thiol pairs in protein samples.

儲存和穩定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

分析報告

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

象形圖

Health hazard

訊號詞

Danger

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 2

1 of 2

Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes
Schmidt M and Dringen R
Frontiers in Neuroenergetics, 1(13), 1-1 (2009)
Proteomic analysis of palmitoylated platelet proteins
Dowal L, et al.
Blood, 118(13), e62-e73 (2011)
Differential Protein Expression in the Nucleus Accumbens and Amygdala of Lewis and Fischer 344 Rats, and its Relevance in Drug Addiction
Roura-Martinez D, et al.
Journal of drug and alcohol research, 6(3), b1-b8 (2014)
COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal
Xu P, et al.
eLife, 6, e28342-e28342 (2017)

实验方案

This page describes typical rehydration solutions for use in gel electrophoresis with GE Healthcare products.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门