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GE17-5072-01

Q Sepharose Xl

Cytiva 17-5072-01, pack of 300 mL

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About This Item

分類程式碼代碼:
41106500
NACRES:
NA.56

ligand

quaternary amine

描述

Ion Exchanger Type (value)

包裝

pack of 300 mL

製造商/商標名

Cytiva 17-5072-01

基質

6% cross-linked agarose with dextran surface extenders

粒徑

45-165 μm

平均直徑

90 μm

cleaning in place

2-14

工作範圍

2-12

適合性

suitable for bioprocess medium

一般說明

Q Sepharose XL is a strong anion exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks.

Q Sepharose XL is based on a highly cross-linked, bead formed 6% agarose matrix similar to the well established Q Sepharose Fast Flow media. Dextran chains are covalently coupled to the agarose matrix and modified with quaternary ammonium (Q) strong anion exchange groups through chemically stable ether bonds. The stable agarose matrix and long, flexible chains of dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates.

With its high loading capacities and excellent physical and chemical stability, Q Sepharose XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples.

As member of the BioProcess media range, Q Sepharose XL meets industrial demands with security of supply and comprehensive technical and regulatory support.

特點和優勢

  • High loading capacities give more productive capture from clarified feedstocks.
  • Strong anion exchanger designed for capture steps
  • High chemical stability for effective CIP/sanitization
  • The hydrophilic nature of the base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool.

儲存和穩定性

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (20% Ethanol)

分析報告

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

法律資訊

Sepharose is a trademark of Cytiva

象形圖

Flame

訊號詞

Warning

危險聲明

儲存類別代碼

3 - Flammable liquids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

This page shows Hydrophobic Interaction Chromatography (HIC) in a purification strategy.

This page shows volatile and non-volatile buffer suggestions for anion and cation exchange chromatography.

This page covers the standard ÄKTAdesign configurations for simple IEX chromatography.

This page shows volatile and non-volatile buffer suggestions for anion and cation exchange chromatography.

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实验方案

This page covers how and when to use Sepharose XL media for purification of proteins.

This page discusses how to do a purification with SOURCE™ media from GE Healthcare

This page shows how to perform column packing and preparation for ion exchange chromatography and chromatafocusing when using Tricorn or XK columns available from GE Healthcare.

This page clarifies sample preparation, buffer exchange and desalting, removal of lipoproteins, phenol red, and low molecular weight contaminants in Ion exchange chromatography.

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