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Merck

G1166

Sigma-Aldrich

Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse

clone GAD-6, purified immunoglobulin, buffered aqueous solution

别名:

Anti-GAD 65

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

GAD-6, monoclonal

形狀

buffered aqueous solution

物種活性

mammals (and some lower vertebrates)

技術

immunohistochemistry: 1:100-1:500
western blot: 1:1,000-1:5,000

同型

IgG2a

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... GAD2(2572)
mouse ... Gad2(14417)

特異性

Recognizes the lower molecular weight isoform of the two GAD isoforms identified in brain, GAD 65. Can be used for immunochemical localization of GABA secreting neurons.

免疫原

purified rat brain GAD 65.

外觀

Solution in 0.01 M phosphate buffered saline, containing 0.04% sodium azide.

準備報告

Purified using Protein A chromatography.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Gregory J Brewer et al.
Frontiers in neural circuits, 7, 165-165 (2013-10-25)
The mammalian hippocampus functions to encode and retrieve memories by transiently changing synaptic strengths, yet encoding in individual subregions for transmission between regions remains poorly understood. Toward the goal of better understanding the coding in the trisynaptic pathway from the
M Esclapez et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 14(3 Pt 2), 1834-1855 (1994-03-01)
Two isoforms of glutamic acid decarboxylase (GAD67 and GAD65) and their mRNAs were localized in the rat brain by immunohistochemistry and nonradioactive in situ hybridization methods with digoxigenin-labeled cRNA probes. In most brain regions, both GAD isoforms were present in
Seung T Lim et al.
The Journal of comparative neurology, 507(2), 1228-1244 (2008-01-09)
Nectins are cell adhesion molecules that, together with the intracellular binding partner afadin, mediate adhesion and signaling at a variety of intercellular junctions. In this work we studied the distribution of nectin-1 and afadin during hippocampal synapse formation using cultured
Ran-Sook Woo et al.
Neuron, 54(4), 599-610 (2007-05-25)
Neuregulin-1 (NRG1), a regulator of neural development, has been shown to regulate neurotransmission at excitatory synapses. Although ErbB4, a key NRG1 receptor, is expressed in glutamic acid decarboxylase (GAD)-positive neurons, little is known about its role in GABAergic transmission. We
Stathis S Leondopulos et al.
Journal of neural engineering, 9(2), 026015-026015 (2012-03-01)
Slow wave oscillations in the brain are essential for coordinated network activity but have not been shown to self-organize in vitro. Here, the development of dissociated hippocampal neurons into an active network with oscillations on multi-electrode arrays was evaluated in

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