所有图片(2)
About This Item
经验公式（希尔记法）:
C27H22O18
CAS号:
分子量:
634.45
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.25
推荐产品
化驗
≥98% (HPLC)
品質等級
形狀
powder
溶解度
H2O: 1 mg/mL, clear, colorless
應用
metabolomics
vitamins, nutraceuticals, and natural products
儲存溫度
2-8°C
SMILES 字串
O[C@@H]1[C@H]2COC(=O)c3cc(O)c(O)c(O)c3-c4c(O)c(O)c(O)cc4C(=O)O[C@@H]1[C@@H](O)[C@@H](O2)OC(=O)c5cc(O)c(O)c(O)c5
InChI
1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2/t13-,19-,22-,23+,27+/m1/s1
InChI 密鑰
TUSDEZXZIZRFGC-XIGLUPEJSA-N
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一般說明
Corilagin is a polyphenolic tannic acid and a major bioactive compound present in various plant species. It is an active component of Phyllanthus urinaria and Terminalia catappa L extract used to treat various ailments.
應用
Corilagin has been used to study its inhibitory effect on the growth of breast cancer by inducing apoptosis and autophagy regulated by the release of reactive oxygen species.
生化／生理作用
Corilagin shows a variety of biological activities such as anti-inflammatory, anti-viral, anti-oxidant, hepatoprotective, antibacterial, anti-coagulant, hypolipemic and hypotensive. It has been noted to possess anti-tumor, antiproliferative, apoptotic, and autophagic abilities as well. Corilagin has been found to reduce the minimum inhibitory concentration (MIC) of β-lactams against Methicillin-resistant Staphylococcus aureus (MRSA).
Corilagin is a polyphenol, specifically a hydrolyzable tannin, found in Traditional Chinese Medicine herbal preparations. It is reported to have anti-inflammatory and anti-tumor activities.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
M Shimizu et al.
Antimicrobial agents and chemotherapy, 45(11), 3198-3201 (2001-10-16)
We found that an extract of Arctostaphylos uva-ursi markedly reduced the MICs of beta-lactam antibiotics, such as oxacillin and cefmetazole, against methicillin-resistant Staphylococcus aureus. We isolated the effective compound and identified it as corilagin. Corilagin reduced the MICs of various
K Nagendra Prasad et al.
Journal of pharmaceutical and biomedical analysis, 51(2), 471-477 (2009-04-07)
The health benefits of fruits acting against chronic diseases are ascribed to their antioxidant activities which are mainly responsible due to the presence of phenolic compounds. The use of ultra-high-pressure-assisted extraction (UHPE) has shown great advantages for the extraction of
Xiaoyu Zhao et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(22), 3137-3140 (2012-03-02)
To establish a RP-HPLC method for the determination of four acids compounds including gallic acid, protocatechuic acid, corilagin and ellagic acid in Erodium Stephanianum. The RP-HPLC separation was performed on an Agilent TC-C18 analytical column (4.6 mm x 250 mm
Nuchanart Rangkadilok et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(2), 328-336 (2006-10-20)
The protective effects of fruits and vegetables against chronic diseases have been attributed to the antioxidant properties of some secondary metabolites present in these foods. Plant polyphenols have been reported to exhibit bioactive properties, and in particular antioxidant activities. Longan
Luoqi Jia et al.
BMC complementary and alternative medicine, 13, 33-33 (2013-02-16)
Phyllanthus niruri L. is a well-known hepatoprotective and antiviral medicinal herb. Recently, we identified Corilagin as a major active component with anti-tumor activity in this herbal medicine. Corilagin is a member of the tannin family that has been discovered in
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