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Key Documents

F1141

Sigma-Aldrich

Bovine Fibronectin

from bovine plasma, liquid, suitable for cell culture

别名:

纤连蛋白 溶液 来源于人类成纤维细胞

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About This Item

EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
eCl@ss:
42020141
NACRES:
NA.75

product name

纤连蛋白牛血浆, solution, sterile-filtered, BioReagent, suitable for cell culture

生物源

bovine plasma

品質等級

無菌

sterile-filtered

產品線

BioReagent

形狀

solution

包裝

pkg of 1 mg
pkg of 2 mg
pkg of 5 mg

技術

cell culture | mammalian: suitable

表面覆盖率

1‑5 μg/cm2

UniProt登錄號

結合特異性

Peptide Source: Collagen

Peptide Source: Fibrinogen

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

bovine ... FN1(280794)

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一般說明

纤连蛋白是一种普遍存在的细胞外基质蛋白。它是一种镶嵌蛋白,由三种的重复模块共有氨基酸序列组成。纤连蛋白属于一类高分子量糖蛋白。细胞纤连蛋白由成纤维细胞表达,血浆纤连蛋白通常由肝细胞释放。

應用

纤连蛋白(FN)牛血浆可用于:
  • 纤连蛋白和吸附分析(ELISA(酶联免疫吸附测定))
  • 跨孔迁移
  • 纤连蛋白测定

生化/生理作用

纤连蛋白参与细胞粘附、细胞骨架组织、致癌性转化、细胞迁移、吞噬、止血和胚胎分化。

分析報告

采用免疫电泳法评估蛋白质的均一性。

其他說明

产品F1141,牛血浆纤连蛋白是pH 7.5的0.05 M TBS溶液。

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves


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Tests to predict preeclampsia
Chesley's Hypertensive Disorders in Pregnancy, 221-251 (2015)
Enhanced fibronectin adsorption on carbon nanotube/poly (carbonate) urethane: independent role of surface nano-roughness and associated surface energy
Khang D, et al.
Biomaterials, 28(32), 4756-4768 (2007)
FIBRONECTIN AUTOANTIBODIES
Autoantibodies, 221-251 (2007)
Role of subnano-, nano-and submicron-surface features on osteoblast differentiation of bone marrow mesenchymal stem cells
Khang D, et al.
Biomaterials, 33(26), 5997-6007 (2012)
Mary Cathleen McKinney et al.
BMC biology, 14(1), 111-111 (2016-12-17)
Collective neural crest cell migration is critical to the form and function of the vertebrate face and neck, distributing bone, cartilage, and nerve cells into peripheral targets that are intimately linked with head vasculature. The vasculature and neural crest structures

商品

Fibronectin (FN) is a multifunctional, extracellular plasma glycoprotein produced by hepatocytes that circulates at near micromolar concentration and assembles into extracellular matrix fibrils at cell surfaces along with locally produced cellular FN.

Attachment Factors for 3-Dimensional Cell Culture

The extracellular matrix (ECM) is secreted by cells and surrounds them in tissues.

3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models

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实验方案

Dilute fibronectin to the desired concentration. Optimum conditions for attachment are dependent on cell type and application. The typical coating concentration is 1 – 5 ug/cm2.Fibronectin coating protocol, products, and FAQs.

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