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Merck
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Key Documents

EHU047921

Sigma-Aldrich

MISSION® esiRNA

targeting human UBR5

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

CAATTCAGCGGGTTTGATTTATATTGATCCTTCAAACTTACGCCGGAGTGGTACCATCAGTACAAGTGCTGCAGCTGCAGCAGCTGCTTTGGAAGCTAGCAACGCCAGCAGTTACCTAACATCTGCAAGCAGTTTAGCCAGGGCTTACAGCATTGTCATTAGACAAATCTCGGACTTGATGGGCCTTATTCCTAAGTATAATCACCTAGTATACTCTCAGATTCCAGCAGCTGTGAAATTGACTTACCAAGATGCAGTAAACTTACAGAACTATGTAGAAGAAAAGCTTATTCCCACTTGGAACTGGATGGTCAGTATTATGGATTCTACTGAAGCTCAATTACGTTATGGTTCTGCATTAGCATCTGCTGGTGATCCTGGACATCCAAATCATCCTCTTCACGCTTCTCAGAATTCAGCGAGAAGAGAGAGGATGACTGCGCGAGAAGAAGCTAG

Ensembl | 人類登錄號

ENSG00000104517

NCBI登錄號

NM_015902

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... UBR5(51366) , UBR5(51366)

相关类别

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Fanghui Ding et al.
Experimental and therapeutic medicine, 20(5), 7-7 (2020-09-17)
The human ubiquitin protein ligase E3 component N-recognin 5 (UBR5) gene, which is localized to chromosome 8q22, encodes an ~10 kb mRNA and a >300 kDa protein, which can be detected in a number of cell types. UBR5 is implicated
Caiyun G Li et al.
Cell reports, 26(5), 1333-1343 (2019-01-31)
Using proteomic approaches, we uncovered a DNA damage response (DDR) function for peroxisome proliferator activated receptor γ (PPARγ) through its interaction with the DNA damage sensor MRE11-RAD50-NBS1 (MRN) and the E3 ubiquitin ligase UBR5. We show that PPARγ promotes ATM

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