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Merck

E7138

Sigma-Aldrich

乙琥胺

别名:

2-乙基-2-甲基琥珀酰亚胺

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About This Item

经验公式(希尔记法):
C7H11NO2
CAS号:
分子量:
141.17
EC號碼:
MDL號碼:
分類程式碼代碼:
12352111
PubChem物質ID:
NACRES:
NA.77

品質等級

溶解度

ethanol: 100 mg/mL

SMILES 字串

O=C1NC(CC1(C)CC)=O

InChI

1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)

InChI 密鑰

HAPOVYFOVVWLRS-UHFFFAOYSA-N

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應用

乙琥胺已被用于:
  • 证实其对大鼠棘波放电(SWD)的作用
  • 考察其对野生型斑马鱼幼体自发运动和焦虑相关趋触性行为的影响
  • 作为模型药物体内治疗癫痫症(4)

生化/生理作用

乙琥胺是一种抗惊厥药,同时也是T型钙通道拮抗剂。它可防止失神发作中的棘波放电。

特點和優勢

该化合物在受体分类和信号转导手册的钙通道页面上有重点介绍。如需浏览其他手册页面,请点击此处

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Behavioural responses of zebrafish larvae to acute ethosuximide exposure
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Behavioural Pharmacology, 28(6), 428-440 (2017)
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Pearce PS, et al.
Epilepsy & Behavior : E&B, 32, 121-131 (2014)
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Epilepsia, 54(1), 141-155 (2012-11-22)
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