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Merck

CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

동의어:
CACNA1HB, Cav3.2, ECA6, EIG6
:
UniProtKB ID:
Clone ID:
  • Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
  • Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit

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Small Molecule - Allosteric Modulator

제품 번호
설명
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Calcium Channel CaV3.2 (α1H) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
종별 반응성
rat
응용분야
western blot
Anti-CACNA1H antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-CACNA1H antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot

Small Molecule - Blocker

제품 번호
설명
Ethosuximide, European Pharmacopoeia (EP) Reference Standard,
human
Trimethadione, European Pharmacopoeia (EP) Reference Standard,
human
Ethosuximide, ,
human
Ethosuximide, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Ethosuximide, United States Pharmacopeia (USP) Reference Standard,
human