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Key Documents

E1378

Sigma-Aldrich

七叶皂苷

≥95%, powder

别名:

七叶皂甙

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About This Item

CAS号:
6805-41-0
EC號碼:
229-880-6
MDL號碼:
MFCD00076054
分類程式碼代碼:
12352201
PubChem物質ID:
24894403
NACRES:
NA.25

生物源

plant (Aesculus chinensis)

品質等級

200

化驗

≥95%

形狀

powder

雜質

≤6.0% Water (Karl Fischer)

顏色

white

溶解度

methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES 字串

C\C=C(/C)C(=O)OC1[C@H](OC(C)=O)C2(CO)[C@H](O)C[C@]3(C)C(=CCC4C5(C)CCC(O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(O)=O)[C@](C)(CO)C5CCC34C)C2CC1(C)C

InChI

1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26?,27-,28-,29?,30?,31-,32?,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43?,44+,47+,48-,49-,51?,52-,53?,54-,55?/m1/s1

InChI 密鑰

AXNVHPCVMSNXNP-YSYFQUGBSA-N

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相关类别

應用

七叶皂苷是从七叶树（ 七叶树 ）种子中分离得到的三萜皂苷的天然混合物，被用作血管保护性抗炎、抗水肿和抗疼痛药物并进行研究。可用于研究其作为 NF-κ 的化疗增敏剂和调节剂的药代动力学、安全性和有效性B 细胞信号传导。

其他說明

为了全面了解我们针对客户研究提供的各种多糖产品，建议您访问我们的碳水化合物分类页面。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302 + H332

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

分析证书(COA)

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Wenyu Xin et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(4), 272-277 (2010-09-21)
Escin, a natural mixture of triterpenoid saponins isolated from the seed of the horse chestnut (Aesculus hippocastanum), had been demonstrated to possess anti-edematous and anti-inflammatory effects. The present study was designed to investigate whether escin exhibits synergistic anti-inflammatory effects when
Xiu-Jun Wu et al.
Journal of ethnopharmacology, 151(2), 839-845 (2013-12-18)
Adequate pharmacokinetic data of escin, a natural mixture of triterpene saponins used for the treatment of chronic venous insufficiency, hemorrhoids, inflammation and edema, is of special interest in view of the growing use of escin agent in clinical medicine. However
Zhenzhen Zhang et al.
Phytotherapy research : PTR, 25(12), 1747-1755 (2011-04-01)
Escin sodium has been used in the clinic as an antioedematous, antiexudative and vasoprotective agent for many years and has shown excellent tolerability. However, little is known about its anticancer activity. This is a report for the first time that
Kuzhuvelil B Harikumar et al.
Molecular pharmacology, 77(5), 818-827 (2010-01-28)
Agents that can enhance tumor cell apoptosis and inhibit invasion have potential for the treatment of cancer. Here, we report the identification of escin, a pentacyclic triterpenoid from horse chestnut that exhibits antitumor potential against leukemia and multiple myeloma. Whether
R W Frick
Angiology, 51(3), 197-205 (2000-04-01)
Escin, hydroxyethylrutoside (HR), and Daflon have been shown to be safe and effective for the treatment of chronic venous insufficiency (CVI). They seem to work differently than compression therapy, suggesting that they would usefully augment this therapy. All three phlebotonics
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