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D9378

Sigma-Aldrich

3,4-二羟基-D-苯丙氨酸

≥95% (TLC), powder, DOPA enantiomer

别名:

3-(3,4-二羟基苯)-D-丙氨酸, D-3-羟基酪氨酸, D-DOPA

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About This Item

经验公式（希尔记法）:
C9H11NO4
CAS号:
5796-17-8
分子量:
197.19
Beilstein:
2417637
EC號碼:
227-343-0
MDL號碼:
MFCD00063061
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
24894286
NACRES:
NA.32

product name

3,4-二羟基-D-苯丙氨酸, powder, ≥95%

品質等級

100

化驗

≥95%

形狀

powder

mp

276-278 °C (lit.)

溶解度

1 M HCl: soluble
ethanol: insoluble

儲存溫度

−20°C

SMILES 字串

N[C@H](Cc1ccc(O)c(O)c1)C(O)=O

InChI

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m1/s1

InChI 密鑰

WTDRDQBEARUVNC-ZCFIWIBFSA-N

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應用

3,4-二羟基-D-苯丙氨酸(D-DOPA)已作为高效液相色谱法(HPLC)标准品，检测刺毛黎豆的发芽和原生种子粉中的L-DOPA。

生化／生理作用

3,4-二羟基-D-苯丙氨酸(D-DOPA)是DOPA的对映体，具有抗菌作用。D-DOPA可作为多巴胺合成的前体。

其他說明

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Nan Lu et al.
Electrophoresis (2020-09-20)
This review summarizes recent developments (over the past decade) in the field of microfluidics-based solutions for enantiomeric separation and detection. The progress in various formats of microchip electrodriven separations, such as MCE, microchip electrochromatography, and multidimensional separation techniques, is discussed.
Mark H Burrell et al.
ACS chemical neuroscience, 6(11), 1802-1812 (2015-09-01)
Tonic dopamine (DA) levels influence the activity of dopaminergic neurons and the dynamics of fast dopaminergic transmission. Although carbon fiber microelectrodes and fast-scan cyclic voltammetry (FSCV) have been extensively used to quantify stimulus-induced release and uptake of DA in vivo
Seppo Parkkila et al.
Bioorganic & medicinal chemistry letters, 16(15), 3955-3959 (2006-05-30)
The first activation study of isoform XIII of carbonic anhydrase (CA, EC 4.2.1.1) is reported. A series of amino acids and amines incorporating protonatable moieties of the primary/heterocyclic amine type were included in the study. As for CA I and
Isao Nishimori et al.
Bioorganic & medicinal chemistry, 15(15), 5351-5357 (2007-05-15)
The secretory isozyme of human carbonic anhydrase (hCA, EC 4.2.1.1), hCA VI, has been cloned, expressed, and purified in a bacterial expression system. The kinetic parameters for the CO(2) hydration reaction proved hCA VI to possess a k(cat) of 3.4
Silvia Pastorekova et al.
Bioorganic & medicinal chemistry, 16(7), 3530-3536 (2008-02-26)
The first activation study of the human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms associated to tumors, hCA IX and XII, with a small library of natural and non-natural amino acids as well as aromatic/heterocyclic amines is reported. hCA IX was
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