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Merck

D7408

Sigma-Aldrich

2′,5′-Dideoxyadenosine

≥95% (HPLC), solid

别名:

2ʹ,5ʹ-dd-Ado, NSC 95943

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About This Item

经验公式(希尔记法):
C10H13N5O2
CAS号:
分子量:
235.24
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥95% (HPLC)

形狀

solid

顏色

white

溶解度

DMSO: soluble

儲存溫度

−20°C

SMILES 字串

C[C@H]1O[C@H](C[C@@H]1O)n2cnc3c(N)ncnc23

InChI

1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1

InChI 密鑰

FFHPXOJTVQDVMO-DSYKOEDSSA-N

基因資訊

應用

2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).

生化/生理作用

Cell-permeable adenylyl cyclase inhibitor. IC50 = 2.7 μM in detergent-dispersed rat brain preparations.

特點和優勢

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

重構

Store at −20 °C after reconstitution.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Journal of Ethnopharmacology, 174, 403-409 (2015)
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