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Merck

D6500

Sigma-Aldrich

2′-脱氧腺苷-5′-三磷酸 二钠盐

≥97%

别名:

数据-Na 2

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About This Item

经验公式(希尔记法):
C10H14N5Na2O12P3
CAS号:
分子量:
535.15
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
eCl@ss:
32160414
PubChem物質ID:
NACRES:
NA.51

生物源

natural (inorganic)

品質等級

化驗

≥97%

形狀

powder

儲存溫度

−20°C

SMILES 字串

[Na+].[Na+].Nc1ncnc2n(cnc12)C3C[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O3

InChI

1S/C10H16N5O12P3.2Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);;/q;2*+1/p-2/t5-,6+,7?;;/m0../s1

InChI 密鑰

JEKDCIBJADJZSK-LNUHRGGJSA-L

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應用

2′-脱氧腺苷 5′-三磷酸二钠盐已用于:
  • Smac-X-连锁凋亡蛋白抑制剂(Smac-XIAP)结合试验。
  • 作为聚合酶链式反应 (PCR) 的组成部分,使用 AM-毒素引物。
  • 测定与转录终止因子Rho的亲和常数 (Kd)。
  • 测定多聚 ADP-核糖聚合酶1(PAPR-1)的活性。
2'-脱氧腺苷-5'-三磷酸 (dATP) 被多种聚合酶(包括 DNA 聚合酶和逆转录酶)用作底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Catalytic Cooperativity among Subunits of Escherichia coli Transcription Termination Factor Rho KINETICS AND SUBSTRATE STRUCTURAL REQUIREMENTS
Browne R J, et al.
The Journal of Biological Chemistry, 280(14), 13292-13299 (2005)
Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64
Cheng J, et al.
American Journal of Human Genetics, 89(1), 56-66 (2011)
J E Reardon
Biochemistry, 31(18), 4473-4479 (1992-05-12)
Steady-state and pre-steady-state kinetic constants were determined for reverse transcriptase catalyzed incorporation of nucleotides and nucleotide analogues into defined-sequence DNA primed-RNA templates. 3'-Azido-3'-deoxythymidine 5'-triphosphate (AZTTP) was almost as efficient a substrate (kcat/Km) as dTTP for the enzyme. In contrast, the
Fadia Haddad et al.
Methods in molecular biology (Clifton, N.J.), 630, 261-270 (2010-03-20)
Reverse transcription (RT) is the synthesis of complementary deoxyribonucleic acids (DNA) from single-stranded ribonucleic acid (RNA) templates. This process is catalyzed by the reverse transcriptase enzyme, which is the replicating enzyme of retroviruses. Reverse transcriptase was discovered in 1970, and
Michael Trostler et al.
Biochemistry, 48(21), 4633-4641 (2009-04-08)
We used a series of dATP and dGTP analogues to determine how DNA polymerase I from Bacillus stearothermophilus (BF), a prototypical A family polymerase, uses N-1, N(2), N-3, and N(6) of purine dNTPs to differentiate between right and wrong nucleotide

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