跳转至内容
Merck
所有图片(3)

Key Documents

更多文件

D4010

Sigma-Aldrich

2′-脱氧鸟苷5′-三磷酸 钠盐 水合物

≥96% (HPLC)

别名:

2′-脱氧-, 5′-三磷酸钠盐, 鸟苷, dGTP 钠盐 水合物

登录查看公司和协议定价
所有图片(3)

About This Item

经验公式（希尔记法）:
C10H16N5O13P3 · xNa+ · yH2O
CAS号:
18423-40-0
分子量:
507.18 (anhydrous free acid basis)
分類程式碼代碼:
41106305
PubChem物質ID:
24893806
NACRES:
NA.51

生物源

synthetic (organic)

化驗

≥96% (HPLC)

形狀

powder

運輸包裝

dry ice

儲存溫度

−20°C

正在寻找类似产品? 访问 产品对比指南

相关类别

應用

2′-脱氧鸟苷5′-三磷酸钠盐水合物已用于：
  • 用作聚合酶链式反应 (PCR) 混合物中的一种成分，使用AM-毒素引物形成 PCR 产物
  • 用作内标，提高毛细管电泳 (CE) 分析的分析性能，评估纯化工艺
  • 用作体外酶活性测定中的推定底物，与Nudix水解酶 15 (NUDT15) 蛋白一起孵育，评估推定的 NUDT15 抑制剂

生化／生理作用

脱氧鸟苷5′-三磷酸(dGTP),一种嘌呤脱氧核糖核苷酸，是DNA聚合酶和逆转录酶的底物。 dGTP可用于研究各种核苷三磷酸酶(NTPase)和核糖核苷酸还原酶的分布、特异性和动力学。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Yogesh A Karpe et al.
PloS one, 6(7), e22336-e22336 (2011-08-04)
Chikungunya virus (CHIKV) is an insect borne virus (genus: Alphavirus) which causes acute febrile illness in humans followed by a prolonged arthralgic disease that affects the joints of the extremities. Re-emergence of the virus in the form of outbreaks in
Yimon Aye et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(24), 9815-9820 (2011-06-02)
Human ribonucleotide reductases (hRNRs) catalyze the conversion of nucleotides to deoxynucleotides and are composed of α- and β-subunits that form active α(n)β(m) (n, m = 2 or 6) complexes. α binds NDP substrates (CDP, UDP, ADP, and GDP, C site)
Rajesh Kasiviswanathan et al.
The Journal of biological chemistry, 286(36), 31490-31500 (2011-07-23)
During DNA synthesis, DNA polymerases must select against ribonucleotides, present at much higher levels compared with deoxyribonucleotides. Most DNA polymerases are equipped to exclude ribonucleotides from their active site through a bulky side chain residue that can sterically block the
Inchul Yang et al.
Analytical biochemistry, 335(1), 150-161 (2004-11-03)
A novel approach for quantitation of DNA (oligonucleotides) with an unprecedented accuracy of approximately 1% is reported. Quantitation of DNA is commonly performed by measuring UV absorption or fluorescence from dyes intercalated into DNA. Both methods need accurate quantitation standards
Si Min Zhang et al.
Cell chemical biology, 28(12), 1693-1702 (2021-07-01)
Ganciclovir (GCV) is the first-line therapy against human cytomegalovirus (HCMV), a widespread infection that is particularly dangerous for immunodeficient individuals. Closely resembling deoxyguanosine triphosphate, the tri-phosphorylated metabolite of GCV (GCV-TP) is preferentially incorporated by the viral DNA polymerase, thereby terminating
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门