推荐产品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
whole antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
包含
15 mM sodium azide
物種活性
rat
包裝
antibody small pack of 25 μL
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
rat ... Calca(24241)
一般說明
降钙素基因相关肽(CGRP)为环状,属于降钙素/CGRP基因复合物编码的一小类肽。降钙素/ CGRP基因复合物由至少两个基因组成,编码两种形式的CGRP:-CGRP(CGRP-I)和-CGRP(CGRP-II)。CGRP在甲状腺滤泡旁C细胞和甲状腺髓样癌中合成,与降钙素共同定位。主要认为其是广泛分布在中枢和外周神经系统的神经肽。
特異性
抗降钙素基因相关肽与 CGRP 反应(大鼠)。观察到与 CGRP(人)和 β-CGRP(人)发生交叉反应。
免疫原
CGRP-KLH
應用
兔抗降钙素基因相关肽抗体用于:
- 斑点印迹免疫测定
- 荧光标记
- 共焦显微镜
- 免疫组化荧光
- 落射荧光成像
兔源抗降钙素基因相关肽抗体可用于三叉神经节细胞培养物的免疫组织化学(1:200稀释),以及小鼠肺切片的免疫细胞化学(1:500稀释)应用。
生化/生理作用
CGRP 被认为是神经递质或神经调节剂,在自主神经(例如心血管、呼吸、胃肠、味觉、食物摄入和睡眠)和边缘功能调节中特别重要。。CGRP 可能与 P 物质共同参与介导神经源性炎症和通过周围神经系统传递疼痛刺激。
降钙素基因相关肽是一种 G 蛋白偶联受体,可结合受体活性修饰蛋白 (RAMP) 1、2 和 3。CLR 与肥胖、糖尿病、骨质疏松症、偏头痛和心血管疾病有关。
數量
脱脂
外觀
以液体形式供应,含 0.1% 叠氮化钠作为防腐剂。
儲存和穩定性
如需连续使用,请存储在2°C至8°C条件下。为延长存储时间,可以将溶液分装冷冻。反复冻融,或在“无霜”条件下储存。不建议使用冰箱。如果长期储存发生轻微浑浊,使用前请离心澄清。
免責聲明
除非我们的目录或产品随附的其他公司文档中另有说明,我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人或动物的任何类型的消费或应用。
Not finding the right product?
Try our 产品选型工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(44), 14649-14656 (2010-11-05)
Pain frequently accompanies cancer. What remains unclear is why this pain frequently becomes more severe and difficult to control with disease progression. Here we test the hypothesis that with disease progression, sensory nerve fibers that innervate the tumor-bearing tissue undergo
Molecular pain, 4, 56-56 (2008-11-19)
Pain is a major symptom associated with chronic inflammation. In previous work from our laboratory, we have shown that in animal models of neuropathic pain there is a sprouting of sympathetic fibers into the upper dermis, a territory normally devoid
Anesthesiology, 121(5), 1068-1079 (2014-07-06)
The aim of this study was to clarify the roles of calcitonin gene-related peptide (CGRP) in postoperative pain and inflammatory pain. αCGRP knockout mice that the authors have developed and wild-type mice were used. Pain behaviors were assessed after incision
British journal of pharmacology, 166(1), 66-78 (2011-08-30)
The clinical effectiveness of antagonizing the calcitonin gene-related peptide (CGRP) receptor for relief of migraine pain has been clearly demonstrated, but the road to the development of these small molecule antagonists has been daunting. The key hurdle that needed to
Physiological reports, 3(12) (2015-12-25)
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is expressed in the epithelium of various primate tissues, including lung airway and alveoli. In human lung, CEACAM6 is developmentally and hormonally regulated, protects surfactant function, has anti-apoptotic activity and is dysregulated in
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门